Nai-Kong V. Cheung

Publications

• Clonal Evolution During Metastatic Spread in High-risk Neuroblastoma
  Nature Genetics. May, 2023  |   Pubmed ID: 37169874
• Identification of Immunotherapy and Radioimmunotherapy Targets on Desmoplastic Small Round Cell Tumors
  Frontiers in Oncology. 2023  |   Pubmed ID: 37091153
• Targeting Tumor Vasculature to Improve Antitumor Activity of T Cells Armed Ex Vivo with T Cell Engaging Bispecific Antibody
  Journal for Immunotherapy of Cancer. Mar, 2023  |   Pubmed ID: 36990507
• Clinical Outcomes of Pediatric Patients Receiving Multimodality Treatment of Second Central Nervous System Relapse of Neuroblastoma
  Pediatric Blood & Cancer. Feb, 2023  |   Pubmed ID: 36349892
• Immunotherapy with Anti-G Monoclonal Antibody in Infants with High-risk Neuroblastoma
  International Journal of Cancer. Jan, 2023  |   Pubmed ID: 35913764
• Skeletal Muscle Metastases in Neuroblastoma Share Common Progenitors with Primary Tumor and Biologically Resemble Stage MS Disease
  Frontiers in Oncology. 2022  |   Pubmed ID: 36686814
• Desmoplastic Small Round Cell Tumor Cancer Stem Cell-like Cells Resist Chemotherapy but Remain Dependent on the EWSR1-WT1 Oncoprotein
  Frontiers in Cell and Developmental Biology. 2022  |   Pubmed ID: 36506091
• Phase 1 Study of Intraventricular I-omburtamab Targeting B7H3 (CD276)-expressing CNS Malignancies
  Journal of Hematology & Oncology. Nov, 2022  |   Pubmed ID: 36371226
• Pretargeting: A Path Forward for Radioimmunotherapy
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Sep, 2022  |   Pubmed ID: 36215514
• Connecting Telomere Maintenance and Regulation to the Developmental Origin and Differentiation States of Neuroblastoma Tumor Cells
  Journal of Hematology & Oncology. Aug, 2022  |   Pubmed ID: 36030273
• Bispecific Antibodies for the Treatment of Neuroblastoma
  Pharmacology & Therapeutics. Sep, 2022  |   Pubmed ID: 35830901
• Overcoming Tumor Heterogeneity by Ex Vivo Arming of T Cells Using Multiple Bispecific Antibodies
  Journal for Immunotherapy of Cancer. Jan, 2022  |   Pubmed ID: 35086947
• Bone Marrow Surveillance of Pediatric Cancer Survivors Identifies Clones That Predict Therapy-Related Leukemia
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2022  |   Pubmed ID: 35078859
• Intraperitoneal Pretargeted Radioimmunotherapy for Colorectal Peritoneal Carcinomatosis
  Molecular Cancer Therapeutics. Jan, 2022  |   Pubmed ID: 34667111
• KMT2A-MAML2 Rearrangement Emerged and Regressed During Neuroblastoma Therapy Without Leukemia After 12.8-year Follow-up
  Pediatric Blood & Cancer. Jan, 2022  |   Pubmed ID: 34550633
• Influence of Fc Modifications and IgG Subclass on Biodistribution of Humanized Antibodies Targeting L1CAM
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Apr, 2022  |   Pubmed ID: 34353869
• Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins
  International Journal of Molecular Sciences. Dec, 2021  |   Pubmed ID: 35008849
• Phase I Trial of Oral Yeast-Derived β-Glucan to Enhance Anti-GD2 Immunotherapy of Resistant High-Risk Neuroblastoma
  Cancers. Dec, 2021  |   Pubmed ID: 34944886
• Immunotherapy and Radioimmunotherapy for Desmoplastic Small Round Cell Tumor
  Frontiers in Oncology. 2021  |   Pubmed ID: 34869013
• Reciprocal Impacts of Telomerase Activity and ADRN/MES Differentiation State in Neuroblastoma Tumor Biology
  Communications Biology. Nov, 2021  |   Pubmed ID: 34799676
• Human Cytomegalovirus Infection Promotes Expansion of a Functionally Superior Cytoplasmic CD3 NK Cell Subset with a Bcl11b-Regulated T Cell Signature
  Journal of Immunology (Baltimore, Md. : 1950). Nov, 2021  |   Pubmed ID: 34625521
• Novel Potent Anti-STEAP1 Bispecific Antibody to Redirect T Cells for Cancer Immunotherapy
  Journal for Immunotherapy of Cancer. Sep, 2021  |   Pubmed ID: 34497115
• Modulating Tumor Infiltrating Myeloid Cells to Enhance Bispecific Antibody-driven T Cell Infiltration and Anti-tumor Response
  Journal of Hematology & Oncology. Sep, 2021  |   Pubmed ID: 34496935
• T Cell Engaging Bispecific Antibodies Targeting CD33 IgV and IgC Domains for the Treatment of Acute Myeloid Leukemia
  Journal for Immunotherapy of Cancer. May, 2021  |   Pubmed ID: 34035113
• Potent Ex Vivo Armed T Cells Using Recombinant Bispecific Antibodies for Adoptive Immunotherapy with Reduced Cytokine Release
  Journal for Immunotherapy of Cancer. May, 2021  |   Pubmed ID: 33986124
• Potent Antitumor Effect of T Cells Armed with Anti-GD2 Bispecific Antibody
  Pediatric Blood & Cancer. Jul, 2021  |   Pubmed ID: 33844437
• Engineered Cells As a Test Platform for Radiohaptens in Pretargeted Imaging and Radioimmunotherapy Applications
  Bioconjugate Chemistry. Apr, 2021  |   Pubmed ID: 33819023
• A Novel Multimeric IL15/IL15Rα-Fc Complex to Enhance Cancer Immunotherapy
  Oncoimmunology. Mar, 2021  |   Pubmed ID: 33763293
• Survival Impact of Anti-GD2 Antibody Response in a Phase II Ganglioside Vaccine Trial Among Patients With High-Risk Neuroblastoma With Prior Disease Progression
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jan, 2021  |   Pubmed ID: 33326254
• IntraOmmaya Compartmental Radioimmunotherapy Using I-omburtamab-pharmacokinetic Modeling to Optimize Therapeutic Index
  European Journal of Nuclear Medicine and Molecular Imaging. Apr, 2021  |   Pubmed ID: 33047248
• A Self-Assembling and Disassembling (SADA) Bispecific Antibody (BsAb) Platform for Curative Two-step Pretargeted Radioimmunotherapy
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2021  |   Pubmed ID: 32958698
• Editorial: Bispecific Antibodies for T-Cell Based Immunotherapy
  Frontiers in Oncology. 2020  |   Pubmed ID: 33363043
• GD2 or HER2 Targeting T Cell Engaging Bispecific Antibodies to Treat Osteosarcoma
  Journal of Hematology & Oncology. Dec, 2020  |   Pubmed ID: 33303017
• Overcoming Leukemia Heterogeneity by Combining T Cell Engaging Bispecific Antibodies
  Journal for Immunotherapy of Cancer. Nov, 2020  |   Pubmed ID: 33239418
• B7H3-Directed Intraperitoneal Radioimmunotherapy With Radioiodinated Omburtamab for Desmoplastic Small Round Cell Tumor and Other Peritoneal Tumors: Results of a Phase I Study
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2020  |   Pubmed ID: 33119478
• Cancer Immunotherapy Via Targeted TGF-β Signalling Blockade in T Cells
  Nature. Nov, 2020  |   Pubmed ID: 33087933
• Pan-neuroblastoma Analysis Reveals Age- and Signature-associated Driver Alterations
  Nature Communications. Oct, 2020  |   Pubmed ID: 33056981
• Alpha Radioimmunotherapy Using Ac-proteus-DOTA for Solid Tumors - Safety at Curative Doses
  Theranostics. 2020  |   Pubmed ID: 33052220
• Reduced-dose Craniospinal Irradiation for Central Nervous System Relapsed Neuroblastoma
  Pediatric Blood & Cancer. Sep, 2020  |   Pubmed ID: 32608559
• Targets and Antibody Formats for Immunotherapy of Neuroblastoma
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2020  |   Pubmed ID: 32167865
• Interdomain Spacing and Spatial Configuration Drive the Potency of IgG-[L]-scFv T Cell Bispecific Antibodies
  Science Translational Medicine. Mar, 2020  |   Pubmed ID: 32161106
• Immunotherapy of Pediatric Solid Tumors: Treatments at a Crossroads, with an Emphasis on Antibodies
  Cancer Immunology Research. Feb, 2020  |   Pubmed ID: 32015013
• An -Acetylgalactosamino Dendron-Clearing Agent for High-Therapeutic-Index DOTA-Hapten Pretargeted Radioimmunotherapy
  Bioconjugate Chemistry. Mar, 2020  |   Pubmed ID: 31891487
• ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition Via Modulation of Neuronal Gene Signatures
  Cancer Cell. Nov, 2019  |   Pubmed ID: 31631027
• Silencing Fc Domains in T Cell-Engaging Bispecific Antibodies Improves T-cell Trafficking and Antitumor Potency
  Cancer Immunology Research. Dec, 2019  |   Pubmed ID: 31615814
• Biodistribution and Dosimetry of Intraventricularly Administered I-Omburtamab in Patients with Metastatic Leptomeningeal Tumors
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Dec, 2019  |   Pubmed ID: 31405921
• Exploiting Signaling Pathways and Immune Targets Beyond the Standard of Care for Ewing Sarcoma
  Frontiers in Oncology. 2019  |   Pubmed ID: 31275859
• Telomere Trimming and DNA Damage As Signatures of High Risk Neuroblastoma
  Neoplasia (New York, N.Y.). Jul, 2019  |   Pubmed ID: 31128432
• Targeted Radioimmunotherapy for Embryonal Tumor with Multilayered Rosettes
  Journal of Neuro-oncology. May, 2019  |   Pubmed ID: 30879172
• Reduced-Dose Radiation Therapy to the Primary Site is Effective for High-Risk Neuroblastoma: Results From a Prospective Trial
  International Journal of Radiation Oncology, Biology, Physics. Jun, 2019  |   Pubmed ID: 30763661
• Theranostic Pretargeted Radioimmunotherapy of Internalizing Solid Tumor Antigens in Human Tumor Xenografts in Mice: Curative Treatment of HER2-positive Breast Carcinoma
  Theranostics. 2018  |   Pubmed ID: 30429889
• Adoptive Immunotherapy with Haploidentical Natural Killer Cells and Anti-GD2 Monoclonal Antibody M3F8 for Resistant Neuroblastoma: Results of a Phase I Study
  Oncoimmunology. 2018  |   Pubmed ID: 30221057
• Development of a Tetravalent Anti-GPA33/Anti-CD3 Bispecific Antibody for Colorectal Cancers
  Molecular Cancer Therapeutics. Oct, 2018  |   Pubmed ID: 30082472
• Convection-enhanced Delivery for Diffuse Intrinsic Pontine Glioma: a Single-centre, Dose-escalation, Phase 1 Trial
  The Lancet. Oncology. Aug, 2018  |   Pubmed ID: 29914796
• A Potent Tetravalent T-cell-engaging Bispecific Antibody Against CD33 in Acute Myeloid Leukemia
  Blood Advances. Jun, 2018  |   Pubmed ID: 29858209
• Treatment and Outcome of Adult-onset Neuroblastoma
  International Journal of Cancer. Sep, 2018  |   Pubmed ID: 29574715
• Dose-escalation is Needed for Gross Disease in High-risk Neuroblastoma
  Pediatric Blood & Cancer. Jul, 2018  |   Pubmed ID: 29469198
• TCR-mimic Bispecific Antibodies Targeting LMP2A Show Potent Activity Against EBV Malignancies
  JCI Insight. Feb, 2018  |   Pubmed ID: 29467338
• Radiation Therapy to Sites of Metastatic Disease As Part of Consolidation in High-Risk Neuroblastoma: Can Long-term Control Be Achieved?
  International Journal of Radiation Oncology, Biology, Physics. Apr, 2018  |   Pubmed ID: 29439882
• Genotyping Natural Killer Immune Checkpoints to Discover Biomarkers of Response
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2018  |   Pubmed ID: 29122934
• Targeting Intracellular Antigens with PMHC-Binding Antibodies: A Phage Display Approach
  Methods in Molecular Biology (Clifton, N.J.). 2018  |   Pubmed ID: 29116509
• A Phase II Study of Radioimmunotherapy with Intraventricular I-3F8 for Medulloblastoma
  Pediatric Blood & Cancer. Jan, 2018  |   Pubmed ID: 28940863
• T Cell Engaging Bispecific Antibody (T-BsAb): From Technology to Therapeutics
  Pharmacology & Therapeutics. Feb, 2018  |   Pubmed ID: 28834699
• -amplified Stage 2/3 Neuroblastoma: Excellent Survival in the Era of Anti-G Immunotherapy
  Oncotarget. Nov, 2017  |   Pubmed ID: 29221128
• Phase I Trial of Anti-GD2 Monoclonal Antibody Hu3F8 Plus GM-CSF: Impact of Body Weight, Immunogenicity and Anti-GD2 Response on Pharmacokinetics and Survival
  Oncoimmunology. 2017  |   Pubmed ID: 29147617
• Erratum to 'Limitations and Opportunities for Immune Checkpoint Inhibitors in Pediatric Malignancies' [Cancer Treat. Rev. 58C (2017) 22-33]
  Cancer Treatment Reviews. Nov, 2017  |   Pubmed ID: 29033261
• Curative Multicycle Radioimmunotherapy Monitored by Quantitative SPECT/CT-Based Theranostics, Using Bispecific Antibody Pretargeting Strategy in Colorectal Cancer
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Nov, 2017  |   Pubmed ID: 28705917
• Bispecific Antibody Does Not Induce T-cell Death Mediated by Chimeric Antigen Receptor Against Disialoganglioside GD2
  Oncoimmunology. 2017  |   Pubmed ID: 28680755
• Limitations and Opportunities for Immune Checkpoint Inhibitors in Pediatric Malignancies
  Cancer Treatment Reviews. Jul, 2017  |   Pubmed ID: 28622628
• A Phase I Study of Single-agent Perifosine for Recurrent or Refractory Pediatric CNS and Solid Tumors
  PloS One. 2017  |   Pubmed ID: 28582410
• Immunotherapy of Hepatocellular Carcinoma Using Chimeric Antigen Receptors and Bispecific Antibodies
  Cancer Letters. Jul, 2017  |   Pubmed ID: 28428075
• Targeted Drug Distribution in Tumor Extracellular Fluid of GD2-expressing Neuroblastoma Patient-derived Xenografts Using SN-38-loaded Nanoparticles Conjugated to the Monoclonal Antibody 3F8
  Journal of Controlled Release : Official Journal of the Controlled Release Society. Jun, 2017  |   Pubmed ID: 28412222
• Overcoming Resistance to HER2-targeted Therapy with a Novel HER2/CD3 Bispecific Antibody
  Oncoimmunology. 2017  |   Pubmed ID: 28405494
• Combination of Bevacizumab, Irinotecan, and Temozolomide for Refractory or Relapsed Neuroblastoma: Results of a Phase II Study
  Pediatric Blood & Cancer. Aug, 2017  |   Pubmed ID: 28111925
• A Phase I/Ib Trial Targeting the Pi3k/Akt Pathway Using Perifosine: Long-term Progression-free Survival of Patients with Resistant Neuroblastoma
  International Journal of Cancer. Jan, 2017  |   Pubmed ID: 27649927
• Temporal Stability and Molecular Persistence of the Bone Marrow Plasma Cell Antibody Repertoire
  Nature Communications. Dec, 2016  |   Pubmed ID: 28000661
• Local Control With 21-Gy Radiation Therapy for High-Risk Neuroblastoma
  International Journal of Radiation Oncology, Biology, Physics. Oct, 2016  |   Pubmed ID: 27473818
• Successful Engineering of a Highly Potent Single-chain Variable-fragment (scFv) Bispecific Antibody to Target Disialoganglioside (GD2) Positive Tumors
  Oncoimmunology. Jun, 2016  |   Pubmed ID: 27471647
• Oncotargets GD2 and GD3 Are Highly Expressed in Sarcomas of Children, Adolescents, and Young Adults
  Pediatric Blood & Cancer. Oct, 2016  |   Pubmed ID: 27304202
• Antitumor Efficacy of Anti-GD2 IgG1 Is Enhanced by Fc Glyco-Engineering
  Cancer Immunology Research. Jul, 2016  |   Pubmed ID: 27197064
• KIR3DL1 Allelic Polymorphism and HLA-B Epitopes Modulate Response to Anti-GD2 Monoclonal Antibody in Patients With Neuroblastoma
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jul, 2016  |   Pubmed ID: 27069083
• Arsenic Trioxide As a Radiation Sensitizer for 131I-Metaiodobenzylguanidine Therapy: Results of a Phase II Study
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Feb, 2016  |   Pubmed ID: 26742708
• Lack of Survival Advantage with Autologous Stem-cell Transplantation in High-risk Neuroblastoma Consolidated by Anti-GD2 Immunotherapy and Isotretinoin
  Oncotarget. Jan, 2016  |   Pubmed ID: 26623730
• Theranostic Pretargeted Radioimmunotherapy of Colorectal Cancer Xenografts in Mice Using Picomolar Affinity ⁸⁶Y- or ¹⁷⁷Lu-DOTA-Bn Binding ScFv C825/GPA33 IgG Bispecific Immunoconjugates
  European Journal of Nuclear Medicine and Molecular Imaging. May, 2016  |   Pubmed ID: 26596724
• Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3
  The Journal of Biological Chemistry. Dec, 2015  |   Pubmed ID: 26487718
• Generation of TCR-Like Antibodies Using Phage Display
  Methods in Molecular Biology (Clifton, N.J.). 2015  |   Pubmed ID: 26424273
• Anti-proliferative and Pro-apoptotic Activity of GD2 Ganglioside-specific Monoclonal Antibody 3F8 in Human Melanoma Cells
  Oncoimmunology. Aug, 2015  |   Pubmed ID: 26405581
• A Distinct Gene Expression Signature Characterizes Human Neuroblastoma Cancer Stem Cells
  Stem Cell Research. Sep, 2015  |   Pubmed ID: 26342562
• Immunotherapy of Childhood Sarcomas
  Frontiers in Oncology. 2015  |   Pubmed ID: 26301204
• Prolonged Progression-free Survival After Consolidating Second or Later Remissions of Neuroblastoma with Anti-G Immunotherapy and Isotretinoin: a Prospective Phase II Study
  Oncoimmunology. Jul, 2015  |   Pubmed ID: 26140243
• Human Derived Dimerization Tag Enhances Tumor Killing Potency of a T-cell Engaging Bispecific Antibody
  Oncoimmunology. Apr, 2015  |   Pubmed ID: 26137406
• Radioimmunotherapy of Human Tumours
  Nature Reviews. Cancer. Jun, 2015  |   Pubmed ID: 25998714
• Low Incidence of Radionecrosis in Children Treated with Conventional Radiation Therapy and Intrathecal Radioimmunotherapy
  Journal of Neuro-oncology. Jun, 2015  |   Pubmed ID: 25944385
• A Dual-specific Anti-IGF-1/IGF-2 Human Monoclonal Antibody Alone and in Combination with Temsirolimus for Therapy of Neuroblastoma
  International Journal of Cancer. Nov, 2015  |   Pubmed ID: 25924852
• Alteration of Electrostatic Surface Potential Enhances Affinity and Tumor Killing Properties of Anti-ganglioside GD2 Monoclonal Antibody Hu3F8
  The Journal of Biological Chemistry. May, 2015  |   Pubmed ID: 25851904
• Chimeric Antigen Receptors and Bispecific Antibodies to Retarget T Cells in Pediatric Oncology
  Pediatric Blood & Cancer. Aug, 2015  |   Pubmed ID: 25832831
• Osteochondroma in Long-term Survivors of High-risk Neuroblastoma
  Cancer. Jun, 2015  |   Pubmed ID: 25728463
• Disialoganglioside GD2 As a Therapeutic Target for Human Diseases
  Expert Opinion on Therapeutic Targets. Mar, 2015  |   Pubmed ID: 25604432
• Bone Marrow Minimal Residual Disease Was an Early Response Marker and a Consistent Independent Predictor of Survival After Anti-GD2 Immunotherapy
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2015  |   Pubmed ID: 25559819
• Retargeting T Cells to GD2 Pentasaccharide on Human Tumors Using Bispecific Humanized Antibody
  Cancer Immunology Research. Mar, 2015  |   Pubmed ID: 25542634
• Antibody Induced Pain in Children: An Opportunity to Study Pain Mechanism, IgG Design and Analgesics
  Pediatric Blood & Cancer. Feb, 2015  |   Pubmed ID: 25382406
• Structural Design of Disialoganglioside GD2 and CD3-bispecific Antibodies to Redirect T Cells for Tumor Therapy
  International Journal of Cancer. Jan, 2015  |   Pubmed ID: 24895182
• GD2-targeted Immunotherapy and Radioimmunotherapy
  Seminars in Oncology. Oct, 2014  |   Pubmed ID: 25440605
• When Overall Survival Fails to Confirm Event-free Survival, Should the Latter Be Used to Set the Standard of Care?
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2014  |   Pubmed ID: 25403224
• Structure Based Refinement of a Humanized Monoclonal Antibody That Targets Tumor Antigen Disialoganglioside GD2
  Frontiers in Immunology. 2014  |   Pubmed ID: 25177320
• Deep MicroRNA Sequencing Reveals Downregulation of MiR-29a in Neuroblastoma Central Nervous System Metastasis
  Genes, Chromosomes & Cancer. Oct, 2014  |   Pubmed ID: 24898736
• Striking Dichotomy in Outcome of MYCN-amplified Neuroblastoma in the Contemporary Era
  Cancer. Jul, 2014  |   Pubmed ID: 24691684
• Key Role for Myeloid Cells: Phase II Results of Anti-G(D2) Antibody 3F8 Plus Granulocyte-macrophage Colony-stimulating Factor for Chemoresistant Osteomedullary Neuroblastoma
  International Journal of Cancer. Nov, 2014  |   Pubmed ID: 24644014
• Imaging the Norepinephrine Transporter in Neuroblastoma: a Comparison of [18F]-MFBG and 123I-MIBG
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2014  |   Pubmed ID: 24573553
• Phase I Trial of a Bivalent Gangliosides Vaccine in Combination with β-glucan for High-risk Neuroblastoma in Second or Later Remission
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2014  |   Pubmed ID: 24520094
• Engineering Anti-GD2 Monoclonal Antibodies for Cancer Immunotherapy
  FEBS Letters. Jan, 2014  |   Pubmed ID: 24295643
• Recurrent Pre-existing and Acquired DNA Copy Number Alterations, Including Focal TERT Gains, in Neuroblastoma Central Nervous System Metastases
  Genes, Chromosomes & Cancer. Dec, 2013  |   Pubmed ID: 24123354
• Anti-GD2 Antibody 3F8 and Barley-derived (1 → 3),(1 → 4)-β-D-glucan: A Phase I Study in Patients with Chemoresistant Neuroblastoma
  Oncoimmunology. Mar, 2013  |   Pubmed ID: 23802080
• Neuroblastoma: Developmental Biology, Cancer Genomics and Immunotherapy
  Nature Reviews. Cancer. Jun, 2013  |   Pubmed ID: 23702928
• In Silico Driven Redesign of a Clinically Relevant Antibody for the Treatment of GD2 Positive Tumors
  PloS One. 2013  |   Pubmed ID: 23696816
• Posterior Reversible Encephalopathy Syndrome in Neuroblastoma Patients Receiving Anti-GD2 3F8 Monoclonal Antibody
  Cancer. Aug, 2013  |   Pubmed ID: 23633099
• Early Negative Minimal Residual Disease in Bone Marrow After Immunotherapy is Less Predictive of Late or Non-marrow Relapse Among Patients with High-risk Stage 4 Neuroblastoma
  Pediatric Blood & Cancer. Jul, 2013  |   Pubmed ID: 23335404
• Ifosfamide, Carboplatin, and Etoposide for Neuroblastoma: a High-dose Salvage Regimen and Review of the Literature
  Cancer. Feb, 2013  |   Pubmed ID: 22951749
• Murine Anti-GD2 Monoclonal Antibody 3F8 Combined with Granulocyte-macrophage Colony-stimulating Factor and 13-cis-retinoic Acid in High-risk Patients with Stage 4 Neuroblastoma in First Remission
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Sep, 2012  |   Pubmed ID: 22869886
• Unlicensed NK Cells Target Neuroblastoma Following Anti-GD2 Antibody Treatment
  The Journal of Clinical Investigation. Sep, 2012  |   Pubmed ID: 22863621
• Humanizing Murine IgG3 Anti-GD2 Antibody M3F8 Substantially Improves Antibody-dependent Cell-mediated Cytotoxicity While Retaining Targeting in Vivo
  Oncoimmunology. Jul, 2012  |   Pubmed ID: 22754766
• Anti-CD3 × anti-GD2 Bispecific Antibody Redirects T-cell Cytolytic Activity to Neuroblastoma Targets
  Pediatric Blood & Cancer. Dec, 2012  |   Pubmed ID: 22707078
• Association of Age at Diagnosis and Genetic Mutations in Patients with Neuroblastoma
  JAMA. Mar, 2012  |   Pubmed ID: 22416102
• Activation of Peripheral-blood Granulocytes is Strongly Correlated with Patient Outcome After Immunotherapy with Anti-GD2 Monoclonal Antibody and Granulocyte-macrophage Colony-stimulating Factor
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Feb, 2012  |   Pubmed ID: 22203761
• Plerixafor Plus Granulocyte-colony Stimulating Factor for Autologous Hematopoietic Stem Cell Mobilization in Patients with Metastatic Neuroblastoma
  Pediatric Blood & Cancer. Mar, 2012  |   Pubmed ID: 21416584
• MYCN and MYC Regulate Tumor Proliferation and Tumorigenesis Directly Through BMI1 in Human Neuroblastomas
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2011  |   Pubmed ID: 21856782
• Successful Multifold Dose Escalation of Anti-GD2 Monoclonal Antibody 3F8 in Patients with Neuroblastoma: a Phase I Study
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2011  |   Pubmed ID: 21343563
• Resectability and Operative Morbidity After Chemotherapy in Neuroblastoma Patients with Encasement of Major Visceral Arteries
  Journal of Pediatric Surgery. Jan, 2011  |   Pubmed ID: 21238649
• Checkpoint Kinase Inhibitor Synergizes with DNA-damaging Agents in G1 Checkpoint-defective Neuroblastoma
  International Journal of Cancer. Oct, 2011  |   Pubmed ID: 21154747
• High-dose Carboplatin-irinotecan-temozolomide: Treatment Option for Neuroblastoma Resistant to Topotecan
  Pediatric Blood & Cancer. Mar, 2011  |   Pubmed ID: 21049517
• Two-compartment Model of Radioimmunotherapy Delivered Through Cerebrospinal Fluid
  European Journal of Nuclear Medicine and Molecular Imaging. Feb, 2011  |   Pubmed ID: 20936407
• High-dose Cyclophosphamide-irinotecan-vincristine for Primary Refractory Neuroblastoma
  European Journal of Cancer (Oxford, England : 1990). Jan, 2011  |   Pubmed ID: 20934323
• Preliminary Results of a Phase I Trial of Prophylactic Ethanol-lock Administration to Prevent Mediport Catheter-related Bloodstream Infections
  Journal of Pediatric Surgery. Oct, 2010  |   Pubmed ID: 20920713
• Differential Impact of High-dose Cyclophosphamide, Topotecan, and Vincristine in Clinical Subsets of Patients with Chemoresistant Neuroblastoma
  Cancer. Jun, 2010  |   Pubmed ID: 20564411
• Neuroblastoma: Therapeutic Strategies for a Clinical Enigma
  Cancer Treatment Reviews. Jun, 2010  |   Pubmed ID: 20227189
• Whole Neuraxis Irradiation to Address Central Nervous System Relapse in High-risk Neuroblastoma
  International Journal of Radiation Oncology, Biology, Physics. Nov, 2010  |   Pubmed ID: 20207502
• High Frequency of P53/MDM2/p14ARF Pathway Abnormalities in Relapsed Neuroblastoma
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2010  |   Pubmed ID: 20145180
• Compartmental Intrathecal Radioimmunotherapy: Results for Treatment for Metastatic CNS Neuroblastoma
  Journal of Neuro-oncology. May, 2010  |   Pubmed ID: 19890606
• Analysis of GD2/GM2 Synthase MRNA As a Biomarker for Small Cell Lung Cancer
  Lung Cancer (Amsterdam, Netherlands). Feb, 2010  |   Pubmed ID: 19457569
• KIR and HLA Genotypes Are Associated with Disease Progression and Survival Following Autologous Hematopoietic Stem Cell Transplantation for High-risk Neuroblastoma
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2009  |   Pubmed ID: 19934297
• Reducing Epitope Spread During Affinity Maturation of an Anti-ganglioside GD2 Antibody
  Journal of Immunology (Baltimore, Md. : 1950). Nov, 2009  |   Pubmed ID: 19812201
• A Focal Lesion in the Falx Cerebri: Harbinger of Classic Stage 4 Neuroblastoma in an Infant Cured Despite Residual Disease After Minimal Therapy
  Pediatric Blood & Cancer. Dec, 2009  |   Pubmed ID: 19711437
• MicroRNA MiR-29 Modulates Expression of Immunoinhibitory Molecule B7-H3: Potential Implications for Immune Based Therapy of Human Solid Tumors
  Cancer Research. Aug, 2009  |   Pubmed ID: 19584290
• Hyperfractionated Low-dose (21 Gy) Radiotherapy for Cranial Skeletal Metastases in Patients with High-risk Neuroblastoma
  International Journal of Radiation Oncology, Biology, Physics. Nov, 2009  |   Pubmed ID: 19427746
• Monoclonal Antibody Therapies for Solid Tumors
  Expert Opinion on Biological Therapy. Mar, 2009  |   Pubmed ID: 19216623
• Specific Gene Expression Profiles and Chromosomal Abnormalities Are Associated with Infant Disseminated Neuroblastoma
  BMC Cancer. Feb, 2009  |   Pubmed ID: 19192278
• Sensitivity of Surveillance Studies for Detecting Asymptomatic and Unsuspected Relapse of High-risk Neuroblastoma
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2009  |   Pubmed ID: 19171710
• Reduced Risk of Secondary Leukemia with Fewer Cycles of Dose-intensive Induction Chemotherapy in Patients with Neuroblastoma
  Pediatric Blood & Cancer. Jul, 2009  |   Pubmed ID: 19148951
• Methionine Depletion with Recombinant Methioninase: in Vitro and in Vivo Efficacy Against Neuroblastoma and Its Synergism with Chemotherapeutic Drugs
  International Journal of Cancer. Apr, 2009  |   Pubmed ID: 19089915
• Management and Outcome of Stage 3 Neuroblastoma
  European Journal of Cancer (Oxford, England : 1990). Jan, 2009  |   Pubmed ID: 18996003
• Exploiting Gene Expression Profiling to Identify Novel Minimal Residual Disease Markers of Neuroblastoma
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2008  |   Pubmed ID: 18980998
• Solitary Relapse of Desmoplastic Small Round Cell Tumor Detected by Positron Emission Tomography/computed Tomography
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2008  |   Pubmed ID: 18809603
• Recurrent Metastatic Neuroblastoma Followed by Myelodysplastic Syndrome: Possible Leukemogenic Role of Temozolomide
  Pediatric Blood & Cancer. Oct, 2008  |   Pubmed ID: 18570300
• Prospective Tracing of MLL-FRYL Clone with Low MEIS1 Expression from Emergence During Neuroblastoma Treatment to Diagnosis of Myelodysplastic Syndrome
  Blood. Apr, 2008  |   Pubmed ID: 18195096
• Transient Sialoadenitis: a Complication of 131I-metaiodobenzylguanidine Therapy
  Pediatric Blood & Cancer. Jun, 2008  |   Pubmed ID: 17973318
• Brain-sparing Radiotherapy for Neuroblastoma Skull Metastases
  Pediatric Blood & Cancer. Jun, 2008  |   Pubmed ID: 17973314
• Distinct FAK-Src Activation Events Promote Alpha5beta1 and Alpha4beta1 Integrin-stimulated Neuroblastoma Cell Motility
  Oncogene. Feb, 2008  |   Pubmed ID: 17828307
• Novel Markers of Subclinical Disease for Ewing Family Tumors from Gene Expression Profiling
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2007  |   Pubmed ID: 18056173
• Phase I Study of Targeted Radioimmunotherapy for Leptomeningeal Cancers Using Intra-Ommaya 131-I-3F8
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2007  |   Pubmed ID: 18048828
• Induction for High-risk Neuroblastoma
  Pediatric Blood & Cancer. Sep, 2007  |   Pubmed ID: 17417798
• Cyclin D1, a Novel Molecular Marker of Minimal Residual Disease, in Metastatic Neuroblastoma
  The Journal of Molecular Diagnostics : JMD. Apr, 2007  |   Pubmed ID: 17384216
• Disialoganglioside Directed Immunotherapy of Neuroblastoma
  Cancer Investigation. Feb, 2007  |   Pubmed ID: 17364560
• High-dose Cyclophosphamide Inhibition of Humoral Immune Response to Murine Monoclonal Antibody 3F8 in Neuroblastoma Patients: Broad Implications for Immunotherapy
  Pediatric Blood & Cancer. Apr, 2007  |   Pubmed ID: 16421906
• Irinotecan Plus Temozolomide for Relapsed or Refractory Neuroblastoma
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Nov, 2006  |   Pubmed ID: 17114661
• Ototoxicity from High-dose Use of Platinum Compounds in Patients with Neuroblastoma
  Cancer. Jul, 2006  |   Pubmed ID: 16779793
• What Factors Predict a Favorable Outcome in Young Children with Disseminated Neuroblastoma?
  Nature Clinical Practice. Oncology. May, 2006  |   Pubmed ID: 16683000
• FCGR2A Polymorphism is Correlated with Clinical Outcome After Immunotherapy of Neuroblastoma with Anti-GD2 Antibody and Granulocyte Macrophage Colony-stimulating Factor
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2006  |   Pubmed ID: 16682723
• Exploiting the MIBG-avidity of Neuroblastoma for Staging and Treatment
  Pediatric Blood & Cancer. Dec, 2006  |   Pubmed ID: 16544298
• Sialyltransferase STX (ST8SiaII): a Novel Molecular Marker of Metastatic Neuroblastoma
  International Journal of Cancer. Jul, 2006  |   Pubmed ID: 16450393
• Liver Involvement in Neuroblastoma: the Memorial Sloan-Kettering Experience Supports Treatment Reduction in Young Patients
  Pediatric Blood & Cancer. Mar, 2006  |   Pubmed ID: 16124002
• Neuroblastoma--from Genetic Profiles to Clinical Challenge
  The New England Journal of Medicine. Nov, 2005  |   Pubmed ID: 16306518
• Radioimmunotargeting of Human Rhabdomyosarcoma Using Monoclonal Antibody 8H9
  Cancer Biotherapy & Radiopharmaceuticals. Oct, 2005  |   Pubmed ID: 16248769
• Prognostic Value of MYCN and ID2 Overexpression in Neuroblastoma
  Pediatric Blood & Cancer. Dec, 2005  |   Pubmed ID: 16047351
• Rituximab Therapy of Lymphoma is Enhanced by Orally Administered (1-->3),(1-->4)-D-beta-glucan
  Leukemia Research. Jun, 2005  |   Pubmed ID: 15863209
• Long-term Complications in Survivors of Advanced Stage Neuroblastoma
  Pediatric Blood & Cancer. Sep, 2005  |   Pubmed ID: 15714447
• Antibody-based Targeted Radiation to Pediatric Tumors
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jan, 2005  |   Pubmed ID: 15653664
• Five-day Courses of Irinotecan As Palliative Therapy for Patients with Neuroblastoma
  Cancer. Feb, 2005  |   Pubmed ID: 15637685
• Characteristics of Stem Cells from Human Neuroblastoma Cell Lines and in Tumors
  Neoplasia (New York, N.Y.). 2004  |   Pubmed ID: 15720811
• Reduction from Seven to Five Cycles of Intensive Induction Chemotherapy in Children with High-risk Neuroblastoma
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Dec, 2004  |   Pubmed ID: 15611504
• Treatment of Neuroblastoma Meningeal Carcinomatosis with Intrathecal Application of Alpha-emitting Atomic Nanogenerators Targeting Disialo-ganglioside GD2
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2004  |   Pubmed ID: 15501978
• Measuring Circulating Neuroblastoma Cells by Quantitative Reverse Transcriptase-polymerase Chain Reaction Analysis
  Cancer. Nov, 2004  |   Pubmed ID: 15484213
• Treatment Reduction for Neuroblastoma
  Pediatric Blood & Cancer. Nov, 2004  |   Pubmed ID: 15390354
• Single-chain Fv-streptavidin Substantially Improved Therapeutic Index in Multistep Targeting Directed at Disialoganglioside GD2
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. May, 2004  |   Pubmed ID: 15136638
• The Impact of Gross Total Resection on Local Control and Survival in High-risk Neuroblastoma
  Journal of Pediatric Surgery. Mar, 2004  |   Pubmed ID: 15017562
• Pharmacokinetics, Dosimetry, and Toxicity of the Targetable Atomic Generator, 225Ac-HuM195, in Nonhuman Primates
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jan, 2004  |   Pubmed ID: 14734685
• Camptothecin Analogs (irinotecan or Topotecan) Plus High-dose Cyclophosphamide As Preparative Regimens for Antibody-based Immunotherapy in Resistant Neuroblastoma
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2004  |   Pubmed ID: 14734455
• Radically Different Treatment Recommendations for Newly Diagnosed Neuroblastoma: Pitfalls in Assessment of Risk
  Journal of Pediatric Hematology/oncology. Jan, 2004  |   Pubmed ID: 14707711
• Treatment of Spinal Involvement in Neuroblastoma Patients
  Pediatric Neurosurgery. Dec, 2003  |   Pubmed ID: 14734862
• Neuroblastoma in Adolescents and Adults: the Memorial Sloan-Kettering Experience
  Medical and Pediatric Oncology. Dec, 2003  |   Pubmed ID: 14595707
• Early Molecular Response of Marrow Disease to Biologic Therapy is Highly Prognostic in Neuroblastoma
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2003  |   Pubmed ID: 14551304
• Anti-idiotypic Antibody Facilitates ScFv Chimeric Immune Receptor Gene Transduction and Clonal Expansion of Human Lymphocytes for Tumor Therapy
  Hybridoma and Hybridomics. Aug, 2003  |   Pubmed ID: 14511566
• Genome-wide Analysis of Gene Expression Associated with MYCN in Human Neuroblastoma
  Cancer Research. Aug, 2003  |   Pubmed ID: 12907629
• Oral Topotecan for Refractory and Relapsed Neuroblastoma: a Retrospective Analysis
  Journal of Pediatric Hematology/oncology. Aug, 2003  |   Pubmed ID: 12902911
• Curability of Recurrent Disseminated Disease After Surgery Alone for Local-regional Neuroblastoma Using Intensive Chemotherapy and Anti-G(D2) Immunotherapy
  Journal of Pediatric Hematology/oncology. Jul, 2003  |   Pubmed ID: 12847316
• Tumor Lysis Syndrome, Neuroblastoma, and Correlation Between Serum Lactate Dehydrogenase Levels and MYCN-amplification
  Medical and Pediatric Oncology. Jul, 2003  |   Pubmed ID: 12764755
• Quantitation of GD2 Synthase MRNA by Real-time Reverse Transcriptase Polymerase Chain Reaction: Clinical Utility in Evaluating Adjuvant Therapy in Neuroblastoma
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2003  |   Pubmed ID: 12637475
• Impact of Metaiodobenzylguanidine Scintigraphy on Assessing Response of High-risk Neuroblastoma to Dose-intensive Induction Chemotherapy
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2003  |   Pubmed ID: 12637474
• Anti-idiotypic Antibody As the Surrogate Antigen for Cloning ScFv and Its Fusion Proteins
  Hybridoma and Hybridomics. Dec, 2002  |   Pubmed ID: 12573107
• Orally Administered Beta-glucans Enhance Anti-tumor Effects of Monoclonal Antibodies
  Cancer Immunology, Immunotherapy : CII. Nov, 2002  |   Pubmed ID: 12384807
• Disialoganglioside GD2 and a Novel Tumor Antigen: Potential Targets for Immunotherapy of Desmoplastic Small Round Cell Tumor
  Medical and Pediatric Oncology. Dec, 2002  |   Pubmed ID: 12376975
• Chronic Neuroblastoma
  Cancer. Sep, 2002  |   Pubmed ID: 12216106
• Evolving Significance of Prognostic Markers Associated with Treatment Improvement in Patients with Stage 4 Neuroblastoma
  Cancer. May, 2002  |   Pubmed ID: 12173347
• Quantitation of GD2 Synthase MRNA by Real-time Reverse Transcription-polymerase Chain Reaction: Utility in Bone Marrow Purging of Neuroblastoma by Anti-GD2 Antibody 3F8
  Cancer. Jun, 2002  |   Pubmed ID: 12115395
• Oral (1-->3),(1-->4)-beta-D-glucan Synergizes with Antiganglioside GD2 Monoclonal Antibody 3F8 in the Therapy of Neuroblastoma
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2002  |   Pubmed ID: 12006541
• Panhandle and Reverse-panhandle PCR Enable Cloning of Der(11) and Der(other) Genomic Breakpoint Junctions of MLL Translocations and Identify Complex Translocation of MLL, AF-4, and CDK6
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2002  |   Pubmed ID: 11930009
• Novel Regions of Allelic Imbalance Identified by Genome-wide Analysis of Neuroblastoma
  Cancer Research. Mar, 2002  |   Pubmed ID: 11912152
• Clinical Categories of Neuroblastoma Are Associated with Different Patterns of Loss of Heterozygosity on Chromosome Arm 1p
  The Journal of Molecular Diagnostics : JMD. Feb, 2000  |   Pubmed ID: 11272900
• Implications of EPHB6, EFNB2, and EFNB3 Expressions in Human Neuroblastoma
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2000  |   Pubmed ID: 10984508
• Detection of Leukemia-associated MLL-GAS7 Translocation Early During Chemotherapy with DNA Topoisomerase II Inhibitors
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2000  |   Pubmed ID: 10706619
• Surface Antigen Expression and Complement Susceptibility of Differentiated Neuroblastoma Clones
  The American Journal of Pathology. Mar, 2000  |   Pubmed ID: 10702424
• Association of CYP3A4 Genotype with Treatment-related Leukemia
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 1998  |   Pubmed ID: 9789061
• Antigen-dependent CD28 Signaling Selectively Enhances Survival and Proliferation in Genetically Modified Activated Human Primary T Lymphocytes
  The Journal of Experimental Medicine. Aug, 1998  |   Pubmed ID: 9705944