Roman J. Szczesny Institute of Biochemistry and Biophysics Polish Academy of Sciences Biography Publications Institution JoVE Articles Roman J. Szczesny has not added a biography. If you are Roman J. Szczesny and would like to personalize this page please email our Author Liaison for assistance. Publications In Vitro Reconstitution Reveals a Key Role of Human Mitochondrial EXOG in RNA Primer Processing Nucleic Acids Research. Aug, 2022 | Pubmed ID: 35819194 Mitochondrial RNA, a New Trigger of the Innate Immune System Wiley Interdisciplinary Reviews. RNA. May, 2022 | Pubmed ID: 34498404 Landscape of Functional Interactions of Human Processive Ribonucleases Revealed by High-throughput SiRNA Screenings IScience. Sep, 2021 | Pubmed ID: 34541468 Human Mitochondrial RNA Processing and Modifications: Overview International Journal of Molecular Sciences. Jul, 2021 | Pubmed ID: 34360765 DNA Repair Protein APE1 Degrades Dysfunctional Abasic MRNA in Mitochondria Affecting Oxidative Phosphorylation Journal of Molecular Biology. Sep, 2021 | Pubmed ID: 34224750 High-Throughput Measurement of Mitochondrial RNA Turnover in Human Cultured Cells Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 33230771 Loading Messenger RNAs Onto Ribosomes in Human Mitochondria: Lessons Learned from a Bacterial Toxin The FEBS Journal. Jan, 2021 | Pubmed ID: 32588551 Human REXO2 Controls Short Mitochondrial RNAs Generated by MtRNA Processing and Decay Machinery to Prevent Accumulation of Double-stranded RNA Nucleic Acids Research. Jun, 2020 | Pubmed ID: 32365187 Mitochondrial Gene Expression and Beyond-Novel Aspects of Cellular Physiology Cells. Dec, 2019 | Pubmed ID: 31861673 Quantitative Proteomics Revealed C6orf203/MTRES1 As a Factor Preventing Stress-induced Transcription Deficiency in Human Mitochondria Nucleic Acids Research. Aug, 2019 | Pubmed ID: 31226201 Controlling the Mitochondrial Antisense - Role of the SUV3-PNPase Complex and Its Co-factor GRSF1 in Mitochondrial RNA Surveillance Molecular & Cellular Oncology. 2018 | Pubmed ID: 30525095 Mitochondrial Double-stranded RNA Triggers Antiviral Signalling in Humans Nature. Aug, 2018 | Pubmed ID: 30046113 Dedicated Surveillance Mechanism Controls G-quadruplex Forming Non-coding RNAs in Human Mitochondria Nature Communications. Jul, 2018 | Pubmed ID: 29967381 Versatile Approach for Functional Analysis of Human Proteins and Efficient Stable Cell Line Generation Using FLP-mediated Recombination System PloS One. 2018 | Pubmed ID: 29590189 Two Novel C-terminal Frameshift Mutations in the β-globin Gene Lead to Rapid MRNA Decay BMC Medical Genetics. Jun, 2017 | Pubmed ID: 28595636 Linear MtDNA Fragments and Unusual MtDNA Rearrangements Associated with Pathological Deficiency of MGME1 Exonuclease Human Molecular Genetics. Dec, 2014 | Pubmed ID: 24986917 Multiple Myeloma-associated HDIS3 Mutations Cause Perturbations in Cellular RNA Metabolism and Suggest HDIS3 PIN Domain As a Potential Drug Target Nucleic Acids Research. Jan, 2014 | Pubmed ID: 24150935 A New Strategy for Gene Targeting and Functional Proteomics Using the DT40 Cell Line Nucleic Acids Research. Sep, 2013 | Pubmed ID: 23892402 Identification of a Novel Human Mitochondrial Endo-/exonuclease Ddk1/c20orf72 Necessary for Maintenance of Proper 7S DNA Levels Nucleic Acids Research. Mar, 2013 | Pubmed ID: 23358826 Human Mitochondrial RNA Decay Mediated by PNPase-hSuv3 Complex Takes Place in Distinct Foci Nucleic Acids Research. Jan, 2013 | Pubmed ID: 23221631 RNA Degradation in Yeast and Human Mitochondria Biochimica Et Biophysica Acta. 2012 | Pubmed ID: 22178375 Human Suv3 Protein Reveals Unique Features Among SF2 Helicases Acta Crystallographica. Section D, Biological Crystallography. Nov, 2011 | Pubmed ID: 22101826 [Final Doctorate Competition 2009. Study of HSuv3p Human Helicase Function] Postepy Biochemii. 2010 | Pubmed ID: 21473039 The Human Core Exosome Interacts with Differentially Localized Processive RNases: HDIS3 and HDIS3L The EMBO Journal. Jul, 2010 | Pubmed ID: 20531386 Human Mitochondrial RNA Turnover Caught in Flagranti: Involvement of HSuv3p Helicase in RNA Surveillance Nucleic Acids Research. Jan, 2010 | Pubmed ID: 19864255 Down-regulation of Human RNA/DNA Helicase SUV3 Induces Apoptosis by a Caspase- and AIF-dependent Pathway Biology of the Cell. Jun, 2007 | Pubmed ID: 17352692 High-Throughput Image-Based Quantification of Mitochondrial DNA Synthesis and Distribution Lukasz S. Borowski1,2, Karolina Kasztelan2,3, Jolanta Czerwinska-Kostrzewska1,2, Roman J. Szczesny2 1Faculty of Biology, Institute of Genetics and Biotechnology, University of Warsaw, 2Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 3International Institute of Molecular and Cell Biology in Warsaw JoVE 65236 Biochimica
High-Throughput Image-Based Quantification of Mitochondrial DNA Synthesis and Distribution Lukasz S. Borowski1,2, Karolina Kasztelan2,3, Jolanta Czerwinska-Kostrzewska1,2, Roman J. Szczesny2 1Faculty of Biology, Institute of Genetics and Biotechnology, University of Warsaw, 2Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 3International Institute of Molecular and Cell Biology in Warsaw JoVE 65236 Biochimica
