The extracellular matrix or ECM holds cells together to form a tissue and allows the cells within the tissue to communicate. ECM comprises proteins…

Animal and protozoan cells do not have cell walls to help maintain shape and provide structural stability. Instead, these eukaryotic cells secrete a…

Integrins bind ligands and transmit information from outside the cell to inside or vice-versa through an "outside-in signaling" or…

Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely…

Anchoring junctions are multiprotein complexes that help cells connect to other cells and the extracellular matrix. Anchoring junctions are present…

In animal cells, the extracellular matrix allows cells within tissues to withstand external stresses and transmits signals from the outside of the…

T lymphocyte adhesion is required for multiple T cell functions, including migration to sites of inflammation and formation of immunological synapses…

Molecular tension transmitted by integrin-ligand bonds is the fundamental mechanical signal in the integrin pathway that plays significant roles in…

The study of how mammalian cell division is regulated in a 3D environment remains largely unexplored despite its physiological relevance and…