Chapter 30
Cell Polarization and Migration
Cell migration is a process by which the cells move from one location to another, playing an essential role in embryological development, repair and…
Actin is a family of globular proteins that are highly abundant in eukaryotic cells. It makes up approximately 1-5% of total cell protein…
The protrusion of the cell surface is an initial step for several cellular processes, including cell migration, phagocytosis, and neurite outgrowth.…
Cells migrating in response to external stimuli form lamellipodia, which are thin membrane protrusions supported by a mesh of linked, branched, or…
Filopodia are thin, actin-rich cellular protrusions that play an important role in many fundamental cellular functions. They vary in their…
Invadosome is a broad category of cell surface structures with proteolytic activity that degrades the extracellular matrix (ECM). Invadosomes…
Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types,…
Myosins are multimeric motor proteins involved in various cellular processes such as migration, adhesion, and proliferation. Myosin II is the most…
Cell polarity is the asymmetric distribution of cellular and membrane components, making one side of the cell different from the other. This polarity…
Cells can detect chemical cues in their environment and reorganize the cytoskeleton to migrate toward them or away from them. This directional…
A migrating cell changes its shape during the cyclic events of attachment and detachment from the substratum and repositions the cell organelles…
Migration is a key property of live cells and critical for normal development, immune response, and disease processes such as cancer metastasis and…
Cells respond to chemokine stimulation by losing their round shape in a process called polarization, and by altering the subcellular localization of…
Myosin proteins bind and interact with filamentous actin (F-actin) and are found in organisms across the phylogenetic tree. Their structure and…
