Nanoparticelle-mediata siRNA silenziamento genico nel cuore di Zebrafish adulto
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09:12 min
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July 29, 2018
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Summary
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Rimane una grande sfida di sviluppare condizionale gene knock-out o efficace gene-atterramento in organi di zebrafish adulto. Qui segnaliamo un protocollo per la performante siRNA nanoparticella-mediata silenziamento genico nel cuore adulto zebrafish, fornendo così un nuovo metodo di perdita di funzione per lo studio di organi adulti in zebrafish e altri organismi di modello.
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Cite this Article
Xiao, C., Wang, F., Hou, J., Zhu, X., Luo, Y., Xiong, J. Nanoparticle-mediated siRNA Gene-silencing in Adult Zebrafish Heart. J. Vis. Exp. (137), e58054, doi:10.3791/58054 (2018).
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