JoVE Journal

Cancer Research

JoVE Cancer Research includes experimental approaches and methods to understand, detect, treat, and prevent cancer.

‹1…5 6 7 › 158 VIDEO ARTICLES

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma (DIPG)

¹Graduate Program in Neuroscience, Department of Neurology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, ²Departments of Neurology, Neurosurgery, Pathology and Pediatrics, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine

JoVE 55360

A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines

Jun Tang¹, Carlos Pérez-Medina^1,2, Yiming Zhao², Ahmad Sadique¹, Willem J. M. Mulder², Thomas Reiner¹

¹Department of Radiology, Memorial Sloan Kettering Cancer Center, ²Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai

JoVE 55271

Live Imaging to Study Microtubule Dynamic Instability in Taxane-resistant Breast Cancers

Richard Wang¹, Harris Wang¹, Zhixiang Wang¹

¹Department of Medical Genetics, Signal Transduction Research Group, Faculty of Medicine and Dentistry, University of Alberta

JoVE 55027

A Rapid Filter Insert-based 3D Culture System for Primary Prostate Cell Differentiation

Lucas Tricoli¹, Deborah L. Berry², Chris Albanese¹

¹Department of Oncology, Lombardi Comprehensive Cancer Center, ²Department of Oncology, Georgetown University Medical Center

JoVE 55279

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Hiren J. Mehta¹, Michael A. Jantz¹

¹Division of Pulmonary/Critical care/Sleep Medicine, University of Florida College of Medicine

JoVE 54855

Intracarotid Cancer Cell Injection to Produce Mouse Models of Brain Metastasis

Chenyu Zhang¹, Frank J. Lowery¹, Dihua Yu¹

¹Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center

JoVE 55085

Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells

Irida Kastrati¹, Loruhama Delgado-Rivera², Gergana Georgieva³, Gregory R. J. Thatcher², Jonna Frasor¹

¹Physiology and Biophysics, College of Medicine, University of Illinois at Chicago, ²Medicinal Chemistry and Pharmacognosy, College of Medicine, University of Illinois at Chicago, ³College of Pharmacy, University of Illinois at Chicago

JoVE 54798

A Murine Orthotopic Bladder Tumor Model and Tumor Detection System

Sin Mun Tham¹, Kesavan Esuvaranathan^1,2, Ratha Mahendran¹

¹Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, ²Department of Urology, National University Hospital

JoVE 55078

Ultrasonographic Evaluation of Breast Cancer-related Lymphedema

Yumi Jeon¹, Jaewon Beom¹, Soyoung Ahn¹, Soo-Kyung Bok¹

¹Department of Rehabilitation Medicine, Chungnam National University Hospital (CNUH)

JoVE 54996

Cell-Free DNA Integrity Analysis in Urine Samples

Valentina Casadio¹, Samanta Salvi¹, Filippo Martignano¹, Roberta Gunelli², Sara Ravaioli¹, Daniele Calistri¹

¹Biosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, ²Department of Urology, Morgagni-Pierantoni Hospital

JoVE 55049

A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma

Phillip Huyett¹, Mark Gilbert¹, Lijun Liu², Robert L. Ferris², Seungwon Kim¹

¹Department of Otolaryngology, University of Pittsburgh Medical Center, ²University of Pittsburgh Cancer Institute, Hillman Cancer Center

JoVE 55043

Hyperpolarized ¹³C Metabolic Magnetic Resonance Spectroscopy and Imaging

Eugen Kubala*^1,2,3, Kim A. Muñoz-Álvarez*¹, Geoffrey Topping¹, Christian Hundshammer^1,2, Benedikt Feuerecker¹, Pedro A. Gómez^3,4, Giorgio Pariani^1,5,6, Franz Schilling¹, Steffen J. Glaser², Rolf F. Schulte³, Marion I. Menzel³, Markus Schwaiger¹

¹Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, ²Department of Chemistry, Technische Universität München, ³GE Global Research, ⁴Zentralinstitut für Medizintechnik der Technischen Universität München (IMETUM), Technische Universität München, ⁵Institute for Biological and Medical Imaging (IBMI), Helmholtz Zentrum München, ⁶IDG Institute of Developmental Genetics, Helmholtz Zentrum München

JoVE 54751

A Portal Vein Injection Model to Study Liver Metastasis of Breast Cancer

Erica T. Goddard¹, Jacob Fischer¹, Pepper Schedin¹

¹Department of Cell, Developmental and Cancer Biology, Oregon Health and Science University

JoVE 54903

Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures

Eamonn Morrison^1,2, Patty Wai^1,2, Andri Leonidou^1,2, Philip Bland^1,2, Saira Khalique^1,2, Gillian Farnie³, Frances Daley¹, Barrie Peck^1,2, Rachael Natrajan^1,2

¹The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer, The Institute of Cancer Research, ²Division of Molecular Pathology, The Institute of Cancer Research, ³Institute of Cancer Sciences, University of Manchester

JoVE 54738

Transduction-Transplantation Mouse Model of Myeloproliferative Neoplasm

Thanh Kim Nguyen¹, Sarah J. Morse¹, Angela G. Fleischman¹

¹Department of Medicine, Division of Hematology/Oncology, University of California, Irvine

JoVE 54624

Using RNA-sequencing to Detect Novel Splice Variants Related to Drug Resistance in In Vitro Cancer Models

Rocco Sciarrillo^1,2,3, Anna Wojtuszkiewicz¹, Irsan E. Kooi⁴, Valentina E. Gómez³, Ugo Boggi⁵, Gerrit Jansen⁶, Gert-Jan Kaspers^1,7, Jacqueline Cloos*¹, Elisa Giovannetti*^3,8,9

¹Department of Pediatric Oncology/Hematology, VU University Medical Center, ²Department of Hematology, VU University Medical Center, ³Department of Medical Oncology, VU University Medical Center, ⁴Department of Clinical Genetics, VU University Medical Center, ⁵Division of General and Transplant Surgery, Azienda Ospedaliera Universitaria Pisana, Universita’ di Pisa, ⁶Amsterdam Immunology and Rheumatology Center, VU University Medical Center, ⁷Princess Máxima Center for Pediatric Oncology, ⁸Cancer Pharmacology Lab, AIRC Start-Up Unit, University of Pisa, ⁹Institute of Nanoscience and Nanotechnology, CNR-Nano

JoVE 54714

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis

Sung-Hyeok Hong*¹, Jason U. Tilan*^2,3, Susana Galli¹, Rachel Acree³, Katherine Connors⁴, Akanksha Mahajan¹, Larissa Wietlisbach³, Taylor Polk³, Ewa Izycka-Swieszewska⁵, Yi-Chien Lee⁶, Luciane R. Cavalli⁶, Olga C. Rodriguez⁶, Chris Albanese^6,7, Joanna B. Kitlinska¹

¹Department of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center, ²Department of Nursing, Georgetown University, School of Nursing and Health Studies, ³Department of Human Science, Georgetown University, School of Nursing and Health Studies, ⁴School of Medicine, Georgetown University Medical Center, ⁵Department of Pathology and Neuropathology, Medical University of Gdańsk, ⁶Department of Oncology, Georgetown University Medical Center, ⁷Department of Pathology, Georgetown University Medical Center

JoVE 54532

Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells

Yoshihiro Koya^1,2, Hiroaki Kajiyama², Wenting Liu^1,2, Kiyosumi Shibata², Takeshi Senga³, Fumitaka Kikkawa²

¹Bell Research Center for Reproductive Health and Cancer, ²Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, ³Department of Cancer Biology, Nagoya University Graduate School of Medicine

JoVE 54353

Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles

Ji-Eun Chang¹, Hyun-Jong Cho², Sanghoon Jheon^1,3

¹Department of Thoracic and Cardiovascular Surgery, Seoul National University Bundang Hospital, ²College of Pharmacy, Kangwon National University, ³Department of Thoracic and Cardiovascular Surgery, Seoul National University College of Medicine

JoVE 54865

Labeling of Breast Cancer Patient-derived Xenografts with Traceable Reporters for Tumor Growth and Metastasis Studies

Colton Hanna¹, Letty Kwok¹, Jessica Finlay-Schultz¹, Carol A. Sartorius¹, Diana M. Cittelly¹

¹Department of Pathology, School of Medicine, University of Colorado Anschutz Medical Campus

JoVE 54944

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia

Andrea Bonetto¹, Joseph E. Rupert¹, Rafael Barreto¹, Teresa A. Zimmers¹

¹Department of Surgery, Simon Cancer Center and IUPUI Center for Cachexia Research, Innovation and Therapy, Indiana University School of Medicine

JoVE 54893

Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones

Go Oshima*^1,2, Melinda E. Stack*¹, Sean C. Wightman¹, Darren Bryan¹, Elizabeth Poli¹, Lai Xue¹, Kinga B. Skowron¹, Abhineet Uppal¹, Sean P. Pitroda², Xiaona Huang², Mitchell C. Posner¹, Samuel Hellman², Ralph R. Weichselbaum², Nikolai N. Khodarev²

¹Department of Surgery, The University of Chicago, ²Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, The University of Chicago

JoVE 54657

Testing the Vascular Invasive Ability of Cancer Cells in Zebrafish (Danio Rerio)

Eric B. Berens¹, Ghada M. Sharif¹, Anton Wellstein¹, Eric Glasgow¹

¹Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University

JoVE 55007

Capture and Release of Viable Circulating Tumor Cells from Blood

Siddarth Rawal¹, Zheng Ao², Ashutosh Agarwal^1,3

¹Department of Pathology, University of Miami, ²SRI International, ³Department of Biomedical Engineering, DJTMF Biomedical Nanotechnology Institute at the University of Miami, University of Miami

JoVE 54435

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