JoVE Journal

Medicine

JoVE Medicine includes methods and experimental approaches for biomedical research and clinical medicine, including case studies, clinical procedures, surgeries, clinical trials, and animal models of disease.

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Press Needle: A Traditional Chinese Medicine Therapy for Myopia Patients with Dry Eye

Tianyao Gong*^1,2, Qun Huang*³, Haiyan Zhang*¹, Chunmeng Liu¹, Xiaojuan Su¹, Yiqi Yang², Xinglin Liu², Yanlin Zheng³, Hejiang Ye³

¹Eye School of Chengdu University of Traditional Chinese Medicine, ²Chengdu University of Traditional Chinese Medicine, ³Hospital of Chengdu University of Traditional Chinese Medicine

JoVE 66727

Endoscopic Balloon Dilatation of the Eustachian Tube via the Soft Palate Approach in Miniature Pigs

Hui Song*^1,2,3,4, Jianping Jia*^1,2,3,4, Danheng Zhao*^1,2,3,4, Mengyuan Guo^1,2,3,4, Fangyuan Wang^1,2,3,4, Kun Hou^1,2,3,4, Nan Jiang⁵, Zhenhao Fu^1,2,3,4, Jingcheng Zhou^1,2,3,4, Haoze Zhang^1,2,3,4, Yulin Ding^1,2,3,4, Yuting Yang⁵, Chen Chen⁵, Xinyuan Jia^1,2,3,4, Zhaohui Hou^1,2,3,4, Shiming Yang^1,2,3,4

¹Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, ²National Clinical Research Center for Otolaryngologic Diseases, ³Key Laboratory of Hearing Science, Ministry of Education, ⁴Beijing Key Laboratory of Hearing Impairment for Prevention and Treatment, ⁵Liaoning University of Traditional Chinese Medicine

JoVE 66609

The Effect of Anti-fatigue Decoction on the Behaviors and Serological Indicators in a Central Fatigue Rat Model

Jie Li¹, Yi Liu¹, Ru-ting Li¹, Yan Liu¹, Feng Li¹

¹School of Traditional Chinese Medicine, Beijing University of Chinese Medicine

JoVE 66481

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized ¹²⁹Xe MRI to Evaluate Lung Structure-Function

Rachel L Eddy^1,2, George H Xu³, Jonathon A Leipsic^1,4, Janice M Leung^1,2, Don D Sin^1,2, Chase S Hall⁵, Roger C Tam^3,4

¹UBC Centre for Heart Lung Innovation, St. Paul’s Hospital, ²Division of Respiratory Medicine, Department of Medicine, University of British Columbia, ³School of Biomedical Engineering, University of British Columbia, ⁴Department of Radiology, University of British Columbia, ⁵Division of Pulmonary and Critical Care Medicine, University of Kansas Medical Center

JoVE 66257

Author Spotlight: Insights into the Effect of Ischemia Reperfusion on Lung Transplantation

Yun Zhu Bai¹, Yuhei Yokoyama¹, Wenjun Li¹, Yuriko Terada¹, Daniel Kreisel¹, Ruben G. Nava¹

¹Division of Cardiothoracic Surgery, Washington University, St. Louis

JoVE 66232

Studying Adipose Endothelial Cell/Adipocyte Cross-Talk in Human Subcutaneous Adipose Tissue

Oliver I. Brown¹, Katherine I. Bridge¹, Sam Straw¹, Natallia Makava¹, Jason Scragg¹, Sunti Limumpornpetch¹, Cheukyau Luk¹, Jessica Smith¹, Anna Skromna¹, Alexander F. Bruns¹, Piruthivi Sukumar¹, Lee D. Roberts¹, Richard Cubbon¹, Klaus K. Witte¹, Stephen Wheatcroft¹, Mark T. Kearney¹

¹Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds

JoVE 66608

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility

Zhouyurong Tan¹, Tsz Ching Yeung¹, Yang Ding¹, Chi Chiu Wang^1,2,3,4

¹Department of Obstetrics and Gynaecology, Faculty of Medicine, The Chinese University of Hong Kong, ²Reproduction and Development, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, ³School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, ⁴Chinese University of Hong Kong-Sichuan University Joint Laboratory in Reproductive Medicine, The Chinese University of Hong Kong

JoVE 66240

Author Spotlight: Segmentation and VR for Advanced Neurovascular Interventions

Reid D. Jockisch¹, Connor R. Davey¹, Sister M. Pieta Keller¹, Sourabh Lahoti², Matthew T. Bramlet³

¹Jump Simulation and Education Center, OSF HealthCare, ²Department of Neurointerventional Surgery and Vascular Neurology, OSF HealthCare, ³Department of Pediatric Cardiology, College of Medicine, University of Illinois, Peoria

JoVE 66227

Metacarpal Small Incision for Carpal Tunnel Syndrome

Jingen Hu^1,2, Caibao Hu³

¹Department of Orthopedics, The First Affiliated Hospital, School of Medicine, Zhejiang University, ²Department of Orthopedics, Liangzhu Branch of the First Affiliated Hospital, School of Medicine, Zhejiang University (The First People's Hospital Of Yuhang District, Hangzhou), ³Intensive Care Unit, Zhejiang Hospital

JoVE 65808

An Intraperitoneal Injection Technique in Adult Zebrafish that Minimizes Body Damage and Associated Mortality

Maryam Moossavi*^1,2, Hong Zhang*^3,4, Jiarong Li^1,2,4, Feixiang Yan^1,2, Xiaolei Xu^1,2

¹Department of Biochemistry and Molecular Biology, Mayo Clinic, ²Department of Cardiovascular Medicine, Mayo Clinic, ³Cardiovascular Surgery Department, Guilin Hospital of 2nd Xiangya Hospital, Central South University, ⁴Cardiovascular Surgery Department, 2nd Xiangya Hospital, Central South University

JoVE 66500

Author Spotlight: Exploring the Relationship Between Lipotoxicity and HFpEF

Monique Williams^1,2, Ali Kamiar^2,3, Jose Manuel Condor Capcha^1,2, Monica Anne Rasmussen⁴, Qusai Alitter², Rosemeire Kanashiro Takeuchi^2,3, Lauro Mitsuru Takeuchi², Joshua M. Hare^1,2, Lina A. Shehadeh^1,2

¹Department of Medicine, Division of Cardiology, University of Miami Leonard M. Miller School of Medicine, ²Interdisciplinary Stem Cell Institute, University of Miami Leonard M. Miller School of Medicine, ³Department of Molecular and Cellular Pharmacology, University of Miami Leonard M. Miller School of Medicine, ⁴Department of Medical Education, University of Miami Leonard M. Miller School of Medicine

JoVE 66442

Author Spotlight: Advancing Diabetes Research with Static Exercise Training in Mice

Mengting Huan*¹, Qingbo Wei*¹, Ying Xie¹, Juan Wei¹, Ting Li¹, Yunchuan Wu¹

¹College of Acupuncture and Massage, Nanjing University of Chinese Medicine

JoVE 65556

Developing a Clinically Relevant Hemorrhagic Shock Model in Rats

Thomas Dupas*¹, Virginie Aillerie*¹, Amandine Vergnaud¹, Thomas Pelé¹, Antoine Persello¹, Angélique Blangy-Letheule¹, Angélique Erraud¹, Mortéza Erfanian¹, Agnès Hivonnait¹, Anaïs Maillard¹, Jules Lecomte², Edith Bigot-Corbel³, Aurélia A. Leroux^1,4, Manon Denis², Bertrand Rozec², Benjamin Lauzier¹

¹CNRS, INSERM, l’institut du thorax, Nantes Université, ²CNRS, INSERM, l’institut du thorax, Nantes Université, CHU Nantes, ³Departement of Biochemistry, CHU de Nantes, ⁴Oniris

JoVE 66523

Remotely Triggered LAD Occlusion Using a Balloon Catheter in Spontaneously Breathing Mice

Michiel Algoet*¹, Matic Pusovnik*², Hilde Gillijns¹, Sien Mestdagh², Janne Billiau¹, Ineke Artoos¹, Willy Gsell², Stefan P. Janssens¹, Uwe Himmelreich², Wouter Oosterlinck¹

¹Department of Cardiovascular Sciences, KU Leuven, ²Biomedical MRI, Department of Imaging and Pathology, KU Leuven

JoVE 66386

Endotracheal Intubation via Tracheotomy and Subsequent Thoracotomy in Rats for Non-Survival Applications

Alexander Studier-Fischer^1,2,3,4, Berkin Özdemir^1,3,4, Karl-Friedrich Kowalewski^2,3,4, Caelan Max Haney^2,3,4,5, Maurice Stephan Michel^2,3,4, Gabriel Alexander Salg¹, Franck Billmann¹

¹Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, ²Department of Urology and Urosurgery, University Medical Center Mannheim, Medical Faculty of the University of Heidelberg, ³Intelligent Systems and Robotics in Urology (ISRU), German Cancer Research Center (DKFZ) Heidelberg, ⁴DKFZ Hector Cancer Institute, University Medical Center Mannheim, ⁵Department of Urology, University Hospital Leipzig

JoVE 66684

Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain

Emily Pettersen^1,2,3,4, Paolo Sassu⁵, Francesca Alice Pedrini^1,5, Hannes Granberg^1,2, Carina Reinholdt^2,6, Juan Manuel Breyer⁷, Aidan Roche⁸, Andrew Hart^9,10, Adil Ladak¹¹, Hollie A. Power¹¹, Michael Leung¹², Michael Lo¹², Ian Valerio¹³, Kyle R. Eberlin¹³, Jason Ko¹⁴, Gregory A. Dumanian¹⁴, Theodore A. Kung¹⁵, Paul Cederna¹⁵, Max Ortiz-Catalan^1,4,16,17

¹Center for Bionics and Pain Research, ²Center for Advanced Reconstruction of Extremities, Sahlgrenska University Hospital, ³Department of Electrical Engineering, Chalmers University of Technology, ⁴Bionics Institute, ⁵IV Clinica Ortoplastica, IRCCS Istituto Ortopedico Rizzoli, ⁶Department of Hand Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, ⁷Department of Orthopedic Surgery, Hand Unit, Worker Hospital, ⁸College of Medicine and Veterinary Medicine, The Queen's Medical Research Institute, The University of Edinburgh, ⁹Canniesburn Plastic Surgery Unit, Glasgow Royal Infirmary, ¹⁰College of Medicine, Veterinary & Life Sciences, The University of Glasgow, ¹¹Division of Plastic Surgery, Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, ¹²Plastics and Reconstructive Surgery, Dandenong Hospital, Monash Health, ¹³Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital & Harvard Medical School, ¹⁴Division of Plastic Surgery, Department of Surgery, Northwestern Feinberg School of Medicine, ¹⁵Section of Plastic Surgery, Department of Surgery, Michigan Medicine, ¹⁶Medical Bionics Department, University of Melbourne, ¹⁷Prometei Pain Rehabilitation Center

JoVE 66378

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease

Da-Chun Jin¹, Yong Luo¹, Peng Wang¹, Yong Zhang¹, Gang Bi¹, Da-Li Tong¹, Yi-Ye Wang¹, Wan-Yi Zhou¹, Yan-Feng Li¹

¹Department of Urology, Army Medical Center, Daping Hospital, Army Medical University

JoVE 66305

Retroperitoneal Laparoscopic Debridement and Drainage for Pancreatic Abscess

Shu-Fan Li¹, Ji-Wei Xu¹, Gao-Min Liu¹, Hua-Dong Zeng¹

¹Department of Hepatobiliary Surgery, Meizhou People’s Hospital

JoVE 66162

Study of Experimental Organ Donation Models for Lung Transplantation

Natalia Aparecida Nepomuceno¹, Liliane Moreira Ruiz¹, Paolo Oliveira-Melo¹, Náthaly Christinie Ikeoka Eroles¹, Isabela Gomes Viana¹, Paulo Manuel Pêgo-Fernandes¹, Karina Andrighetti de Oliveira Braga¹

¹Laboratório de Pesquisa em Cirurgia Torácica, Departamento de Cardiopneumologia, Instituto do Coracao, Faculdade de Medicina HCFMUSP, Universidade de São Paulo

JoVE 62975

Heterotopic Auxiliary Whole Liver Rat Transplant Model Utilizing a Hepaticoureterostomy for Allograft Rejection Studies

Bret Verhoven¹, Weifeng Zeng², Peter Chlebeck¹, Kristina Matkowskyj^3,4,5, Heather Jennings¹, Samuel Poore², David Al-Adra¹

¹Department of Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, ²Department of Surgery, Division of Plastic and Reconstructive Surgery, University of Wisconsin, ³Department of Pathology and Laboratory Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, ⁴UW Carbone Cancer Center, ⁵William S. Middleton Memorial Veterans' Hospital

JoVE 66516

Targeted Muscle Reinnervation: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain

Emily Pettersen^1,2,3,4, Paolo Sassu⁵, Francesca Alice Pedrini^1,5, Hannes Granberg^1,2, Carina Reinholdt^2,6, Juan Manuel Breyer⁷, Aidan Roche⁸, Andrew Hart^9,10, Adil Ladak¹¹, Hollie A. Power¹¹, Michael Leung¹², Michael Lo¹², Ian Valerio¹³, Kyle R. Eberlin¹³, Theodore A. Kung¹⁴, Paul Cederna¹⁴, Jason M. Souza^15,16, Oskar Aszmann¹⁷, Jason Ko¹⁸, Gregory A. Dumanian¹⁸, Max Ortiz-Catalan^1,4,19,20