JoVE Journal

Neuroscience

JoVE Neuroscience is devoted to the study of the brain and nervous system; also featuring potential treatments for neurological diseases.

‹1 2 3 4 5 6 7 8 9…41 › 973 VIDEO ARTICLES

An In Vivo Blood-brain Barrier Permeability Assay in Mice Using Fluorescently Labeled Tracers

Kavi Devraj^1,2, Sylvaine Guérit¹, Jakranka Macas¹, Yvonne Reiss¹

¹Institute of Neurology (Edinger Institute), Goethe University Hospital, ²Pharmazentrum Frankfurt, Institute for General Pharmacology and Toxicology, Goethe University Hospital

JoVE 57038

Preparation of Acute Brain Slices Using an Optimized N-Methyl-D-glucamine Protective Recovery Method

Jonathan T. Ting*¹, Brian R. Lee*¹, Peter Chong¹, Gilberto Soler-Llavina¹, Charles Cobbs², Christof Koch¹, Hongkui Zeng¹, Ed Lein¹

¹Cell Types Program, Allen Institute for Brain Science, ²The Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment, Swedish Neuroscience Institute

JoVE 53825

Retrograde Neuroanatomical Tracing of Phrenic Motor Neurons in Mice

Jean-Michel Vandeweerd¹, Fanny Hontoir¹, Alexis De Knoop¹, Kathleen De Swert², Charles Nicaise²

¹URVI, NARILIS, Université de Namur, ²URPhyM, NARILIS, Université de Namur

JoVE 56758

Monitoring the Effect of Osmotic Stress on Secretory Vesicles and Exocytosis

Hoda Fathali¹, Johan Dunevall¹, Soodabeh Majdi², Ann-Sofie Cans¹

¹Department of Chemistry and Chemical Engineering, Chalmers University of Technology, ²Department of Chemistry and Molecular Biology, University of Gothenburg

JoVE 56537

Using a Microfluidics Device for Mechanical Stimulation and High Resolution Imaging of C. elegans

Holger Fehlauer*¹, Adam L. Nekimken*^1,2, Anna A. Kim^1,2, Beth L. Pruitt^1,2,3, Miriam B. Goodman^1,2, Michael Krieg⁴

¹Department of Molecular and Cellular Physiology, Stanford University, ²Department of Mechanical Engineering, Stanford University, ³Department of Bioengineering, Stanford University, ⁴Group of Neurophotonics and Mechanical Systems Biology, The Institute of Photonic Sciences (ICFO)

JoVE 56530

Characterization and Isolation of Mouse Primary Microglia by Density Gradient Centrifugation

Jessica C. Stark*¹, Euan Wallace^1,2, Rebecca Lim¹, Bryan Leaw*¹

¹The Ritchie Centre, Hudson Institute of Medical Research, ²Department of Obstetrics & Gynaecology, Monash University

JoVE 57065

Examining Monosynaptic Connections in Drosophila Using Tetrodotoxin Resistant Sodium Channels

Xiaonan Zhang¹, Quentin Gaudry¹

¹Department of Biology, University of Maryland

JoVE 57052

Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1

Yi-Chen Lee^1,2, Shui-Chin Lu³, Yu-Lin Hsieh^1,2

¹Department of Anatomy, School of Medicine, College of Medicine, Kaohsiung Medical University, ²Department of Medical Research, Kaohsiung Medical University Hospital, ³Department of Medical Research, Ultrastructural Laboratory, Kaohsiung Medical University Hospital

JoVE 56651

Online Transcranial Magnetic Stimulation Protocol for Measuring Cortical Physiology Associated with Response Inhibition

Michael D. Guthrie¹, Donald L. Gilbert², David A. Huddleston², Ernest V. Pedapati^2,3, Paul S. Horn², Stewart H. Mostofsky⁴, Steve W. Wu²

¹College of Medicine, University of Cincinnati, ²Division of Neurology, Cincinnati Children's Hospital Medical Center, ³Division of Psychiatry, Cincinnati Children's Hospital Medical Center, ⁴Center for Neurodevelopmental and Imaging Research, Kennedy Krieger Institute

JoVE 56789

Ratiometric Calcium Imaging of Individual Neurons in Behaving Caenorhabditis Elegans

Bhavya Ravi*¹, Layla M. Nassar*^1,2, Richard J. Kopchock III*², Pravat Dhakal*², Michael Scheetz², Kevin M. Collins^1,2

¹Neuroscience Program, University of Miami School of Medicine, ²Department of Biology, University of Miami

JoVE 56911

In Vivo Electrophysiological Measurement of the Rat Ulnar Nerve with Axonal Excitability Testing

Brandon M. Wild¹, Renée Morris¹, Mihai Moldovan², Christian Krarup², Arun V. Krishnan³, Ria Arnold¹

¹School of Medical Science, University of New South Wales, ²Department of Clinical Neurophysiology, Rigshospitalet and the Institute of Neuroscience and Pharmacology, University of Copenhagen, ³Prince of Wales Clinical School, University of New South Wales

JoVE 56102

Simple Generation of a High Yield Culture of Induced Neurons from Human Adult Skin Fibroblasts

Shelby Shrigley¹, Karolina Pircs¹, Roger A. Barker^1,2, Malin Parmar¹, Janelle Drouin-Ouellet¹

¹Department of Experimental Medical Science, Wallenberg Neuroscience Center, Division of Neurobiology and Lund Stem Cell Center, Lund University, ²John van Geest Centre for Brain Repair & Department of Neurology, Department of Clinical Neurosciences and Cambridge Stem Cell Institute, University of Cambridge

JoVE 56904

A Novel In Vitro Live-imaging Assay of Astrocyte-mediated Phagocytosis Using pH Indicator-conjugated Synaptosomes

Youkyeong Gloria Byun¹, Won-Suk Chung¹

¹Department of Biological Sciences, Korea Advanced Institute of Science and Technology

JoVE 56647

Neuroimaging Field Methods Using Functional Near Infrared Spectroscopy (NIRS) Neuroimaging to Study Global Child Development: Rural Sub-Saharan Africa

Kaja K. Jasińska^1,2, Sosthène Guei³

¹Linguistics and Cognitive Science Department, University of Delaware, ²Haskins Laboratories, ³Centre de Recherche et d'Action pour la Paix

JoVE 57165

The Mouse Hindbrain As a Model for Studying Embryonic Neurogenesis

Mathew Tata¹, Christiana Ruhrberg¹

¹UCL Institute of Ophthalmology

JoVE 56793

Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia

Rebecca B Beck*¹, Eavan M McGovern*^1,2,3, John S Butler⁴, Dorina Birsanu¹, Brendan Quinlivan¹, Ines Beiser^1,2,3, Shruti Narasimham¹, Sean O'Riordan^2,3, Michael Hutchinson^2,3, Richard B Reilly^1,5

¹School of Engineering, Trinity College Dublin, The University of Dublin, ²Department of Neurology, St. Vincent's University Hospital, ³School of Medicine and Medical Sciences, University College Dublin, ⁴School of Mathematical Sciences, Dublin Institute of Technology, ⁵School of Medicine Trinity College Dublin, The University of Dublin

JoVE 56310

Isolation and Cultivation of Neural Progenitors Followed by Chromatin-Immunoprecipitation of Histone 3 Lysine 79 Dimethylation Mark

Patrick Bovio^1,2, Deborah Roidl¹, Stefanie Heidrich¹, Tanja Vogel¹, Henriette Franz¹

¹Institute for Anatomy and Cell Biology, Department of Molecular Embryology, Faculty of Medicine, University of Freiburg, ²Faculty of Biology, University of Freiburg

JoVE 56631

Quantitative Measurement of γ-Secretase-mediated Amyloid Precursor Protein and Notch Cleavage in Cell-based Luciferase Reporter Assay Platforms

Bo-Jeng Wang*¹, Pei-Yi Wu*¹, Yun-Wen Chen*¹, Yu-Tzu Chang¹, Noopur Bhore¹, Po-Fan Wu¹, Yung-Feng Liao¹

¹Laboratory of Molecular Neurobiology, Institute of Cellular and Organismic Biology, Academia Sinica

JoVE 56795

Personalized Needles for Microinjections in the Rodent Brain

Giovanna Paolone*¹, Chiara Falcicchia*¹, Gianluca Verlengia*¹, Mario Barbieri¹, Anna Binaschi¹, Federico Paliotto¹, Beatrice Paradiso¹, Marie Soukupova¹, Silvia Zucchini^1,2, Michele Simonato^1,2

¹Department of Medical Sciences, Section of Pharmacology, and National Institute of Neurosciences, University of Ferrara, ²Laboratory for the Technologies for Advanced Therapies (LTTA), University of Ferrara

JoVE 55751

Visualization of Cortical Modules in Flattened Mammalian Cortices

Simon M. Lauer*¹, Undine Schneeweiß¹, Michael Brecht^1,2,3, Saikat Ray*¹

¹Bernstein Center for Computational Neuroscience, Humboldt University of Berlin, ²NeuroCure Cluster of Excellence, ³German Center for Neurodegenerative Diseases

JoVE 56992

In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model

Symantas Ragauskas¹, Eva Kielczewski², Joseph Vance^2,3, Simon Kaja^1,4, Giedrius Kalesnykas¹

¹Experimentica Ltd., ²Leica Microsystems, ³Spective LLC, ⁴Department of Ophthalmology, Stritch School of Medicine, Loyola University Chicago

JoVE 56173

Single-cell Resolution Fluorescence Live Imaging of Drosophila Circadian Clocks in Larval Brain Culture

Virginie Sabado¹, Emi Nagoshi¹

¹Department of Genetics and Evolution, University of Geneva

JoVE 57015

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Katharina Schregel^1,2, Daniel Behme¹, Ioannis Tsogkas¹, Michael Knauth¹, Ilko Maier³, André Karch⁴, Rafael Mikolajczyk^4,5, Mathias Bähr³, Jörn Schäper⁶, José Hinz⁶, Jan Liman³, Marios-Nikos Psychogios¹

¹Institute of Neuroradiology, University Medical Center Goettingen, ²Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, ³Department of Neurology, University Medical Center Goettingen, ⁴Department of Epidemiology, Helmholtz Center for Infection Research, ⁵Institute of Medical Epidemiology, Biostatistics and Informatics, Martin-Luther-University Halle-Wittenberg, ⁶Department of Anesthesiology, University Medical Center Goettingen

JoVE 56397

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Mahmoud Messerer¹, Giulia Cossu¹, Mercy George², Roy Thomas Daniel¹

¹Department of Neurosurgery, University Hospital of Lausanne, ²Department of Otorhinolaryngology, University Hospital of Lausanne

JoVE 55896

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