JoVE Journal

Neuroscience

JoVE Neuroscience includes methods and techniques for studying the brain and nervous system; also featuring potential treatments for neurological conditions and diseases.

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Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors

Yu Yamanoi^1,2,3,4, Hiroki Kittaka^1,2,5, Makoto Tominaga^1,2,3,6

¹Thermal Biology Group, Exploratory Research Center on Life and Living Systems (ExCELLS), ²Division of Cell Signaling, National Institute for Physiological Sciences, ³Department of Physiological Sciences, Graduate University for Advanced Studies (SOKENDAI), ⁴Research Laboratory, Ikedamohando Co., Ltd., ⁵Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, ⁶Institute for Environmental and Gender-Specific Medicine, Juntendo University

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking

Oscar W.H. Wong¹, Gabriel P.C. Fung², Sandra Chan¹

¹Department of Psychiatry, The Chinese University of Hong Kong, ²Lab Viso Limited

Time-lapse Live Imaging and Quantification of Fast Dendritic Branch Dynamics in Developing Drosophila Neurons

Chengyu Sheng¹, Uzma Javed¹, Justin Rosenthal¹, Jun Yin¹, Bo Qin¹, Quan Yuan¹

¹National Institute of Neurological Disorders and Stroke, National Institutes of Health

In Vivo Intracerebral Stereotaxic Injections for Optogenetic Stimulation of Long-Range Inputs in Mouse Brain Slices

Louis Richevaux^1,2, Louise Schenberg^1,2, Mathieu Beraneck^1,2, Desdemona Fricker^1,2

¹CNRS (Integrative Neuroscience and Cognition Center, UMR 8002), ²Université Paris Descartes, Sorbonne Paris Cité

The Detection of 5-Hydroxymethylcytosine in Neural Stem Cells and Brains of Mice

Yingliang Zhuang^1,2, Junchen Chen^1,2, Weize Xu¹, Qiang Shu¹, Xuekun Li^1,2

¹The Children's Hospital, School of Medicine, Zhejiang University, ²The Institute of Translational Medicine, School of Medicine, Zhejiang University

Investigating Alterations in Caecum Microbiota After Traumatic Brain Injury in Mice

Liang Wen*¹, Wendong You*¹, Yadong Wang*¹, Yuanrun Zhu¹, Hao Wang¹, Xiaofeng Yang¹

¹Emergency and Trauma Center, The International Medical Center, The First Affiliated Hospital, School of Medicine, Zhejiang University

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome

Makoto Takahashi¹, Akiko Shinya¹, Yuki Choh¹, Sakiko Itaya¹, Akira Inaba¹, Satoshi Orimo¹

¹Department of Neurology, Kanto Central Hospital

Visualizing Astrocyte Morphology Using Lucifer Yellow Iontophoresis

Stefanie L. Moye¹, Blanca Diaz-Castro¹, Mohitkumar R. Gangwani¹, Baljit S. Khakh^1,2

¹Department of Physiology, David Geffen School of Medicine, University of California Los Angeles, ²Department of Neurobiology, David Geffen School of Medicine, University of California Los Angeles

Rapid Isolation of Dorsal Root Ganglion Macrophages

Xiaobing Yu¹, Jacqueline Leff¹, Zhonghui Guan¹

¹Department of Anesthesia and Perioperative Care, University of California San Francisco

Identifying Cell Surface Markers of Primary Neural Stem and Progenitor Cells by Metabolic Labeling of Sialoglycan

Qing-Ran Bai*¹, Lu Dong*², Qin Shen¹

¹Brain and Spinal Cord Innovative Research Center of Tongji Hospital, School of Life Sciences and Technology, Tongji University and Frontier Science Research Center for Stem Cells of Ministry of Education, ²College of Chemistry and Molecular Engineering, Peking-Tsinghua Center for Life Sciences, Beijing National Laboratory for Molecular Sciences, Synthetic and Functional Biomolecules Center, and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Peking University

Generation of Neurospheres from Mixed Primary Hippocampal and Cortical Neurons Isolated from E14-E16 Sprague Dawley Rat Embryo

Gaurav Das^1,2, Varsha Gupta¹, Juhee Khan¹, Deepshikha Mukherjee¹, Surajit Ghosh^1,2

¹Organic and Medicinal Chemistry Division, CSIR-Indian Institute of Chemical Biology, ²Academy of Scientific and Innovative Research (AcSIR)

Visualizing and Analyzing Intracellular Transport of Organelles and Other Cargos in Astrocytes

Blake A. Creighton*¹, Theodore W. Ruffins*¹, Damaris N. Lorenzo¹

¹Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill

Stochastic Noise Application for the Assessment of Medial Vestibular Nucleus Neuron Sensitivity In Vitro

Sebastian P. Stefani^1,2, Paul P. Breen³, Jorge M. Serrador⁴, Aaron J. Camp^1,2

¹Discipline of Physiology, Sydney Medical School, University of Sydney, ²Bosch Institute, Sydney Medical School, University of Sydney, ³The MARCS Institute, Western Sydney University, ⁴Department of Pharmacology, Physiology & Neuroscience, Rutgers Biomedical and Health Sciences

Post-differentiation Replating of Human Pluripotent Stem Cell-derived Neurons for High-content Screening of Neuritogenesis and Synapse Maturation

Barbara Calabrese^1,2, Regina M. Powers^1,2, Alexandria J. Slepian^1,2, Shelley Halpain^1,2

¹Division of Biological Sciences, University of California, San Diego, ²Sanford Consortium for Regenerative Medicine

Use of In Vivo Single-fiber Recording and Intact Dorsal Root Ganglion with Attached Sciatic Nerve to Examine the Mechanism of Conduction Failure

Honghui Mao*^1,2, Xiuchao Wang*^1,3, Wen Chen⁴, FengYu Liu⁵, You Wan⁵, Sanjue Hu¹, Junling Xing^1,6

¹Department of Neurobiology, School of Basic Medicine, Fourth Military Medical University, ²Department of Toxicology, School of Public Health, ShanXi Medical University, ³Department of Psychology, Fourth Military Medical University, ⁴Department of Neurobiology, School of Basic Medical Sciences, Advanced Innovation Center for Human Brain Protection, Capital Medical University, ⁵Neuroscience Research Institute, Key Lab for Neuroscience, Ministry of Education/National Health Commission, Peking University, ⁶Department of Radiation Biology, Faculty of Preventive Medicine, Fourth Military Medical University

Transplantation of Chemogenetically Engineered Cortical Interneuron Progenitors into Early Postnatal Mouse Brains

Myrto Denaxa^1,2, Guilherme Neves³, Juan Burrone³, Vassilis Pachnis¹

¹Nervous System Development and Homeostasis Laboratory, The Francis Crick Institute, ²Neuroscience Centre, Biomedical Sciences Research Centre "Al. Fleming", ³Centre for Developmental Neurobiology, King's College London

Non-invasive Strategies for Chronic Manipulation of DREADD-controlled Neuronal Activity

Jesse Zhan¹, Ruchi Komal¹, William T. Keenan², Samer Hattar¹, Diego C. Fernandez¹

¹Section on Light and Circadian Rhythms (SLCR), National Institute of Mental Health, ²Howard Hughes Medical Institute, Department of Neuroscience, Scripps Research Institute

A Minimally Invasive Lesion Technique for Muscles Intrinsic to the Odontophore of Aplysia californica

Catherine Kehl¹, Hillel J. Chiel^1,2,3,4

¹Department of Biology, Case Western Reserve University, ²Department of Biology, Case Western Reserve University, ³Department of Neurosciences, Case Western Reserve University, ⁴Department of Biomedical Engineering, Case Western Reserve University

Murine Model of Controlled Cortical Impact for the Induction of Traumatic Brain Injury

Steven J Schwulst¹, Mecca B.A.R. Islam¹

¹Department of Surgery, Northwestern University

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury

Kim Braeckman¹, Benedicte Descamps¹, Christian Vanhove¹

¹Infinity lab, Medical Imaging and Signal Processing Group, Ghent University

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Bradford Z. Mahon^1,2, Jeffrey A. Mead³, Benjamin L Chernoff², Maxwell H. Sims⁵, Frank E. Garcea⁴, Emily Prentiss⁵, Raouf Belkhir², Sam J. Haber¹, Sarah B. Gannon⁵, Steve Erickson⁵, Kelly A. Wright⁵, Michael Z. Schmidt⁵, Audrey Paulzak¹, Vanessa C. Milano¹, David A. Paul¹, Kenneth Foxx¹, Madalina Tivarus^7,8, Jacob W. Nadler⁶, Jacqueline M Behr¹, Susan O. Smith¹, Yan Michael Li¹, Kevin Walter¹, Webster H. Pilcher¹

¹Department of Neurosurgery, University of Rochester Medical Center, ²Department of Psychology, Carnegie Mellon University, ³Public Relations and Communications, University of Rochester Medical Center, ⁴MOSS Rehabilitation Research Institute, Cognitive Neuroscience, ⁵University of Rochester Medical Center, ⁶Department of Anesthesiology and Perioperative Medicine, University of Rochester Medical Center, ⁷Department of Imaging Sciences, University of Rochester Medical Center, ⁸Department of Neuroscience, University of Rochester Medical Center

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording

Hannnah Tetteh*¹, Jihwan Lee*¹, Jinho Lee², Jae Geun Kim³, Sunggu Yang²

¹Department of Biomedical Sciences, City University of Hong Kong, ²Department of Nano-Bioengineering, Incheon National University, ³Division of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University

Hybrid Microdrive System with Recoverable Opto-Silicon Probe and Tetrode for Dual-Site High Density Recording in Freely Moving Mice

Hisayuki Osanai¹, Takashi Kitamura^1,2, Jun Yamamoto¹

¹Department of Psychiatry, University of Texas Southwestern Medical Center, ²Department of Neuroscience, University of Texas Southwestern Medical Center

Electrophysiological Investigations of Retinogeniculate and Corticogeniculate Synapse Function

Xufeng Chen¹, Danni Wang¹, Marcel Kegel¹, Jakob von Engelhardt¹

¹Institute of Pathophysiology, University Medical Center of the Johannes Gutenberg University Mainz

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