JoVE Journal

Neuroscience

JoVE Neuroscience includes methods and techniques for studying the brain and nervous system; also featuring potential treatments for neurological conditions and diseases.

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Effects of Transcranial Alternating Current Stimulation on the Primary Motor Cortex by Online Combined Approach with Transcranial Magnetic Stimulation

Anna Shpektor^1,3, Maria Nazarova⁴, Matteo Feurra^1,2

¹School of Psychology, Centre for Cognition and Decision Making, National Research University Higher School of Economics, ²Department of Medicine, Surgery and Neuroscience, Unit of Neurology and Clinical Neurophysiology, Brain Investigation & Neuromodulation Lab. (Si-BIN Lab), Azienda Ospedaliera Universitaria of Siena, ³Department of Experimental Psychology, University of Oxford, ⁴Centre for Cognition and Decision Making, National Research University Higher School of Economics

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo

Jolanta Jagodzinska*¹, Emmanuelle Sarzi*¹, Mélanie Cavalier¹, Marie Seveno¹, Volker Baecker², Christian Hamel^1,3,4, Marie Péquignot¹, Cecile Delettre¹

¹INSERM U1051, Institut of Neurosciences of Montpellier, ²CNRS UMS3426, BioCampus Montepellier, ³University of Montpellier, ⁴CHRU Montpellier, Centre of Reference for Genetic Sensory Diseases, CHU Gui de Chauliac Hospital

Assessment of Dopaminergic Homeostasis in Mice by Use of High-performance Liquid Chromatography Analysis and Synaptosomal Dopamine Uptake

Kathrine L. Jensen¹, Annika H. Runegaard¹, Pia Weikop², Ulrik Gether¹, Mattias Rickhag¹

¹Molecular Neuropharmacology and Genetics Laboratory, Lundbeck Foundation Center for Biomembranes in Nanomedicine, Department of Neuroscience and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, ²Laboratory of Neuropsychiatry, Psychiatric Center Copenhagen and Department of Neuroscience and Pharmacology, University of Copenhagen

Modelling Zika Virus Infection of the Developing Human Brain In Vitro Using Stem Cell Derived Cerebral Organoids

Max R Salick*¹, Michael F Wells*^2,3, Kevin Eggan^2,3, Ajamete Kaykas¹

¹Department of Neuroscience, Novartis Institutes for BioMedical Research, ²Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, ³Department of Stem Cell and Regenerative Biology and Harvard Stem Cell Institute, Harvard University

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

Bryony L. McGarry*¹, Kimmo T. Jokivarsi*², Michael J. Knight¹, Olli H.J. Grohn², Risto A. Kauppinen¹

¹School of Experimental Psychology and Clinical Research and Imaging Center Bristol, University of Bristol, ²Department of Neurobiology, A.I. Virtanen Institute, University of Eastern Finland

Touchscreen Sustained Attention Task (SAT) for Rats

Debra A. Bangasser^1,2, Brittany Wicks¹, David E. Waxler¹, Samantha R. Eck¹

¹Psychology Department, Temple University, ²Neuroscience Program, Temple University

Measuring In Vivo Changes in Extracellular Neurotransmitters During Naturally Rewarding Behaviors in Female Syrian Hamsters

Kelsey M. Moore¹, Brett T Himmler¹, Benjamin A Teplitzky², Matthew D Johnson^2,3, Robert L Meisel¹

¹Department of Neuroscience, University of Minnesota, ²Department of Biomedical Engineering, University of Minnesota, ³Institute for Translational Neuroscience, University of Minnesota

Stereotactic Atlas-Guided Laser Capture Microdissection of Brain Regions Affected by Traumatic Injury

Harris A. Weisz*¹, Deborah R. Boone*¹, Stacy L. Sell¹, Helen L. Hellmich¹

¹Department of Anesthesiology, University of Texas Medical Branch

Using an Adapted Microfluidic Olfactory Chip for the Imaging of Neuronal Activity in Response to Pheromones in Male C. Elegans Head Neurons

Douglas K. Reilly¹, Daniel E. Lawler², Dirk R. Albrecht^1,2, Jagan Srinivasan¹

¹Department of Biology and Biotechnology, Worcester Polytechnic Institute, ²Department of Biomedical Engineering, Worcester Polytechnic Institute

Measuring Synaptic Vesicle Endocytosis in Cultured Hippocampal Neurons

Seth Villarreal¹, Sung Hoon Lee^1,2, Ling-Gang Wu¹

¹National Institute of Neurological Disorders and Stroke, ²College of Pharmacy, Chung-ang University

Stereological Estimation of Dopaminergic Neuron Number in the Mouse Substantia Nigra Using the Optical Fractionator and Standard Microscopy Equipment

Chi Wang Ip¹, David Cheong¹, Jens Volkmann¹

¹Department of Neurology, University Hospital of Würzburg

Electroencephalographic, Heart Rate, and Galvanic Skin Response Assessment for an Advertising Perception Study: Application to Antismoking Public Service Announcements

Giulia Cartocci¹, Myriam Caratù², Enrica Modica³, Anton Giulio Maglione¹, Dario Rossi³, Patrizia Cherubino⁴, Fabio Babiloni¹

¹Department of Molecular Medicine, Sapienza University of Rome, ²Department of Communication and Social Research, Sapienza University of Rome, ³Department of Anatomical, Histological, Forensic, and Orthopedic Sciences, Sapienza University of Rome, ⁴BrainSigns SRL

Organotypic Hippocampal Slice Cultures As a Model to Study Neuroprotection and Invasiveness of Tumor Cells

Urszula Grabiec*¹, Tim Hohmann*¹, Niels Hammer², Faramarz Dehghani¹

¹Department of Anatomy and Cell Biology, Martin Luther University Halle-Wittenberg, ²Department of Anatomy, University of Otago

Methods and Tips for Intravenous Administration of Adeno-associated Virus to Rats and Evaluation of Central Nervous System Transduction

Mychal S. Grames¹, Kasey L. Jackson¹, Robert D. Dayton¹, John A. Stanford², Ronald L. Klein¹

¹Department of Pharmacology, Toxicology, and Neuroscience, Louisiana State University Health Sciences Center, ²Department of Molecular & Integrative Physiology, University of Kansas Medical Center

A Protocol for the Administration of Real-Time fMRI Neurofeedback Training

Matthew S. Sherwood^1,2, Emily E. Diller², Elizabeth Ey³, Subhashini Ganapathy^2,4, Jeremy T. Nelson⁵, Jason G. Parker^1,6

¹Office of the Vice President for Research and Graduate Studies, Wright State University, ²Department of Biomedical, Industrial and Human Factors Engineering, Wright State University, ³Pediatric Radiology and Medical Imaging, Dayton Children's Hospital, ⁴Department of Trauma Care and Surgery, Boonshoft School of Medicine, Wright State University, ⁵Department of Defense Hearing Center of Excellence, JBSA-Lackland, ⁶Department of Neurology, Boonshoft School of Medicine, Wright State University

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins

Sung-Soo Jang^1,2, Han Gil Jeong¹, Hee Jung Chung^1,2

¹Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, ²Neuroscience Program, University of Illinois at Urbana-Champaign

Recombinant α- β- and γ-Synucleins Stimulate Protein Phosphatase 2A Catalytic Subunit Activity in Cell Free Assays

Sovanarak Lek¹, Javier Vargas-Medrano¹, Ernesto Villanueva¹, Brian S. Marcus¹, Wesley Godfrey¹, Ruth G. Perez¹

¹Department of Biomedical Sciences, Center of Emphasis in Neurosciences, Graduate School of Biomedical Sciences, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso

Development of a Refined Protocol for Trans-scleral Subretinal Transplantation of Human Retinal Pigment Epithelial Cells into Rat Eyes

Cuiping Zhao¹, Nathan C. Boles¹, Justine D. Miller¹, Suzanne Kawola¹, Sally Temple¹, Richard J. Davis*¹, Jeffrey H. Stern*¹

¹Neural Stem Cell Institute

Live Imaging of Primary Cerebral Cortex Cells Using a 2D Culture System

Bruna Soares Landeira¹, Jéssica Alves de Medeiros Araújo¹, Timm Schroeder², Ulrich Müller³, Marcos R. Costa¹

¹Brain Institute, Federal University of Rio Grande do Norte, ²Department of Biosystems Science and Engineering, ETH Zurich, ³The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University

Measuring Neuromuscular Junction Functionality

Emanuele Rizzuto¹, Simona Pisu², Carmine Nicoletti², Zaccaria Del Prete^1,3, Antonio Musarò^2,3

¹Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, ²Institute Pasteur Cenci-Bolognetti, DAHFMO-Unit of Histology and Medical Embryology, Sapienza University of Rome, ³Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia

The Use of Trace Eyeblink Classical Conditioning to Assess Hippocampal Dysfunction in a Rat Model of Fetal Alcohol Spectrum Disorders

Tuan D. Tran^1,2, Aenia Amin^1,2, Keith G. Jones², Ellen M. Sheffer¹, Lidia Ortega¹, Keith Dolman²

¹Department of Psychology, East Carolina University, ²Multidisciplinary Studies Program in Neuroscience, East Carolina University

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Laura M. J. Fernandez¹, Sandro Lecci¹, Romain Cardis¹, Gil Vantomme¹, Elidie Béard¹, Anita Lüthi¹

¹Department of Fundamental Neurosciences, University of Lausanne

Tuning in the Hippocampal Theta Band In Vitro: Methodologies for Recording from the Isolated Rodent Septohippocampal Circuit

Frédéric Manseau¹, Sylvain Williams¹

¹Department of Psychiatry, Douglas Mental Health University Institute, McGill University

Assessment and Communication for People with Disorders of Consciousness

Rupert Ortner¹, Brendan Z. Allison¹, Gerald Pichler², Alexander Heilinger³, Nikolaus Sabathiel¹, Christoph Guger^1,3

¹Guger Technologies OG, ²Albert Schweitzer Hospital Graz, ³g.tec Medical Engineering GmbH

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