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Antigens, CD3: Complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (Receptors, Antigen, T-Cell). The Cd3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the Cd3 complex transduces the activating signals to the cytoplasm of the T-cell. The Cd3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (Receptors, Antigen, T-Cell, Gamma-delta).
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