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Cell Differentiation: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.

An In Vivo Mouse Model to Measure Naïve CD4 T Cell Activation, Proliferation and Th1 Differentiation Induced by Bone Marrow-derived Dendritic Cells

1LamImSys Lab, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 2LamImSys Lab, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), 3CIBER de Enfermedades Cardiovasculares

JoVE 58118


 Immunology and Infection

Human Pluripotent Stem Cell Culture on Polyvinyl Alcohol-Co-Itaconic Acid Hydrogels with Varying Stiffness Under Xeno-Free Conditions

1Department of Chemical and Materials Engineering, National Central University, 2Department of Botany and Microbiology, King Saud University, 3Cathay Medical Research Institute, Cathay General Hospital, 4Graduate Institute of Systems Biology and Bioinformatics, National Central University, 5Department of Medical Microbiology and Parasitology, Universiti Putra Malaysia, 6Department of Internal Medicine, Taiwan Landseed Hospital, 7Department of Zoology, Bharathiar University, 8Thiruvalluvar University

JoVE 57314


 Bioengineering

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model

1Department of Otolaryngology Head & Neck Surgery, Nationwide Children's Hospital, 2The Ohio State University College of Medicine, 3Center for Regenerative Medicine, Research Institute at Nationwide Children's Hospital, 4Center for Perinatal Research, Nationwide Children's Hospital, 5Nanofiber Solutions, Inc., 6Department of Pediatric Surgery, Nationwide Children's Hospital

Video Coming Soon

JoVE 59173


 JoVE In-Press

Wet-spinning-based Molding Process of Gelatin for Tissue Regeneration

1Department of Materials Sciences and Engineering, National Taiwan University of Science and Technology, 2Lab of Adult Stem Cell and Tissue Regeneration, National Defense Medical Center, 3School of Dentistry, National Yang-Ming University, 4Department and Graduate Institute of Biology and Anatomy, National Defense Medical Center, 5Department of Gerontological Health Care, National Taipei University of Nursing and Health Sciences, 6Division of Rheumatology/Immunology/Allergy, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, 7Department of Physiology and Biophysics, Graduate Institute of Physiology, National Defense Medical Center, 8Division of Urology, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center

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JoVE 58932


 JoVE In-Press

Neurogenesis Using P19 Embryonal Carcinoma Cells

1Department of Experimental Embryology, The Institute of Genetics and Animal Breeding, Polish Academy of Sciences, 2Division of Animal Reproduction, ICAR-Indian Veterinary Research Institute, 3Department of Regenerative Medicine, Maria Sklodowska-Curie Institute - Oncology Center, 4Department of Genomics and Biodiversities, The Institute of Genetics and Animal Breeding, Polish Academy of Sciences, 5Research Centre for Nano-Bioscience, Doshisha University

Video Coming Soon

JoVE 58225


 JoVE In-Press

Flow Cytometric Detection of Newly-Formed Breast Cancer Stem Cell-like Cells After Apoptosis Reversal

1School of Life Sciences, Chinese University of Hong Kong, 2State Key Laboratory of Agrobiotechnology, Chinese University of Hong Kong, 3Key Laboratory for Regenerative Medicine, Ministry of Education, Chinese University of Hong Kong, 4Centre for Novel Biomaterials, Chinese University of Hong Kong

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JoVE 58642


 JoVE In-Press

Evaluation of Biomarkers in Glioma by Immunohistochemistry on Paraffin-Embedded 3D Glioma Neurosphere Cultures

1Department of Neurosurgery, University of Michigan Medical School, 2Department of Cell & Developmental Biology, University of Michigan, 3INIBIOLP, Histology B-Pathology B, School of Medicine, UNLP

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JoVE 58931


 JoVE In-Press

A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-Specific Thymic Emigrants

1Surgery Branch, National Cancer Institute, NIH, 2Center for Cell-Based Therapy, National Cancer Institute, NIH, 3Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, NIH

Video Coming Soon

JoVE 58672


 JoVE In-Press

Isolation and Characterization of Human Umbilical Cord-derived Mesenchymal Stem Cells from Preterm and Term Infants

1Department of Pediatrics, Kobe University Graduate School of Medicine, 2Department of Pathology, Kobe Children's Hospital, 3Department of Pediatrics, Hyogo College of Medicine, 4Department of Developmental Pediatrics, Shizuoka Children's Hospital, 5Department of Pediatrics, Nihon University School of Medicine

Video Coming Soon

JoVE 58806


 JoVE In-Press

In Vitro Differentiation of Mouse Granulocyte-macrophage-colony-stimulating Factor (GM-CSF)-producing T Helper (THGM) Cells

1Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 2Immunology Programme, Life Sciences Institute, National University of Singapore, 3Cancer Science Institute of Singapore, Yong Loo Lin School of Medicine, National University of Singapore

JoVE 58087


 Immunology and Infection

Engineering Transplantation-suitable Retinal Pigment Epithelium Tissue Derived from Human Embryonic Stem Cells

1U861, I-Stem, Association Française contre les Myopathies (AFM), Institut National de la Santé et de la Recherche Médicale (INSERM), 2U861, I-Stem, Association Française contre les Myopathies (AFM), Université Evry Val-d'Essonne (UEVE), 3I-Stem, Association Française contre les Myopathies (AFM), Centre pour L’Etude des Cellules Souches (CECS), 4Banque de tissus humain, Hôpital Saint Louis, Assistance Publique - Hôpitaux de Paris (AP-HP), 5Sorbonne Université, INSERM, CNRS, Institut de la Vision, F-75012

JoVE 58216


 Developmental Biology

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