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Crossing Over, Genetic: The reciprocal exchange of segments at corresponding positions along pairs of homologous Chromosomes by symmetrical breakage and crosswise rejoining forming cross-over sites (Holliday junctions) that are resolved during Chromosome segregation. Crossing-over typically occurs during Meiosis but it may also occur in the absence of meiosis, for example, with bacterial chromosomes, organelle chromosomes, or somatic cell nuclear chromosomes.
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