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Cyclin-Dependent Kinase 4: Cyclin-dependent kinase 4 is a key regulator of G1 phase of the Cell cycle. It partners with Cyclin d to phosphorylate Retinoblastoma protein. Cdk4 activity is inhibited by Cyclin-dependent kinase inhibitor p16.

Isolation and Immortalization of Patient-derived Cell Lines from Muscle Biopsy for Disease Modeling

1Department of Cell Biology, UT Southwestern Medical Center, 2National Institute of Neurological Disorders and Stroke, National Institute of Health, 3Division of Pediatric Pathology, Department of Pathology and Laboratory Medicine, Medical College of Wisconsin, 4Division of Genetics and Genomics, Boston Children's Hospital

JoVE 52307


 Medicine

Isolation of Cerebral Capillaries from Fresh Human Brain Tissue

1Sanders-Brown Center on Aging, Department of Pharmacology and Nutritional Sciences, University of Kentucky, 2Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 3Department of Neuroscience, University of Kentucky

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JoVE 57346


 JoVE In-Press

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