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 JoVE Immunology and Infection

Pairwise Growth Competition Assay for Determining the Replication Fitness of Human Immunodeficiency Viruses

1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 3,4, 1,2

1Department of Microbiology, University of Washington, 2Departments of Medicine and Laboratory Medicine, University of Washington, 3U.S Military HIV Research Program, Walter Reed Army Institute of Research, 4Henry M. Jackson Foundation


JoVE 52610

 JoVE Immunology and Infection

Protocols for Investigating the Host-tissue Distribution, Transmission-mode, and Effect on the Host Fitness of a Densovirus in the Cotton Bollworm

1, 2, 3, 1, 1

1State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, 2Tobacco Research Institute, Chinese Academy of Agricultural Sciences, 3Crop and Environment Sciences, Harper Adams University


JoVE 55534

 JoVE Environment

Mass Production of Genetically Modified Aedes aegypti for Field Releases in Brazil

1,2, 1, 1, 1, 1, 3, 3, 4, 1,5, 2,6

1Oxitec Ltd, 2Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, 3Departamento de Epidemiologia, Universidade de São Paulo, 4Moscamed Brasil, 5Deptartment of Zoology, University of Oxford, 6Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular (INCT-EM)


JoVE 3579

 JoVE Biology

Competitive Genomic Screens of Barcoded Yeast Libraries

*1,2, *2,3, *4, 1,2, 5, 2,3, 2,6, 1,2,3

1Banting and Best Department of Medical Research and Department of Molecular Genetics, University of Toronto, 2Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 3Donnelly Sequencing Centre, University of Toronto, 4Genetics and Molecular Biology Branch, National Human Genome Research Institute, NIH, 5Stanford Genome Technology Center, Stanford School of Medicine, Stanford University, 6Department of Pharmaceutical Sciences, University of Toronto


JoVE 2864

 JoVE In-Press

Empirical, Metagenomic, and Computational Techniques Illuminate the Mechanisms by Which Fungicides Compromise Bee Health

1,2, 2, 3,4, 5, 1,3, 6,7,8

1Vegetable Crop Research Unit, USDA-ARS, 2Department of Entomology, University of Wisconsin-Madison, 3Department of Horticulture, University of Wisconsin-Madison, 4Instituto Nacional de Investigaciones Forestales, Agricolas y Pecuarias, 5Department of Bacteriology, University of Wisconsin-Madison, 6Laboratory of Genetics, Genome Center of Wisconsin, 7DOE Great Lakes Bioenergy Research Center, Wisconsin Energy Institute, 8J.F. Crow Institute for the Study of Evolution, University of Wisconsin-Madison

Video Coming Soon

JoVE 54631

 JoVE Medicine

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis

1, 1,2, 1, 1, 3, 1, 4, 4, 1,2,4

1Motion Analysis Laboratory, Kennedy Krieger Institute, 2Physical Medicine & Rehabilitation, Johns Hopkins University School of Medicine, 3Johns Hopkins University School of Medicine, 4Department of Neurology, Johns Hopkins University School of Medicine


JoVE 53449

 Science Education: Essentials of Experimental Psychology

Placebos in Research

JoVE Science Education

Source: Laboratories of Gary Lewandowski, Dave Strohmetz, and Natalie Ciarocco—Monmouth University

Clinical research focuses on the efficacy of treatments for addressing disorders and illnesses. A challenge with this type of research is that participants often have pre-existing beliefs about the treatment, particularly expectations that the treatment will work. Though it has been practiced around the world for centuries, yoga is a relatively recent fitness craze in the United States with a wide range of alleged benefits, including the belief that it improves one’s creativity. However, it is not always clear whether yoga is actually creating the benefits, like improved creativity, or the yoga practitioner’s expectations are really the cause. This video demonstrates a two-group design that examines whether a person who believes he or she is doing yoga (but in reality is not) experiences similar benefits to a person who actually does yoga. Specifically, this study looks at whether there is a placebo effect such that merely believing you are doing yoga benefits creativity.  Psychological studies often use higher sample sizes than studies in other sciences. A large number of participants help…

 JoVE Bioengineering

Training Persons with Spinal Cord Injury to Ambulate Using a Powered Exoskeleton

1, 1, 1, 2, 1

1Department of Veterans Affairs (VA) Rehabilitation Research and Development National Center of Excellence for the Medical Consequences of Spinal Cord Injury, James J. Peters VA Medical Center, 2Department of Veterans Affairs (VA) Spinal Cord Injury Service, James J. Peters VA Medical Center


JoVE 54071

 JoVE In-Press

Generation of Escape Variants of Neutralizing Influenza Virus Monoclonal Antibodies

1,2, 1,2, 1,2, 3, 3, 1, 1

1Department of Microbiology, Icahn School of Medicine at Mount Sinai, 2Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, 3The Department of Medicine, Section of Rheumatology, The Knapp Center for Lupus and Immunology Research, The University of Chicago

Video Coming Soon

JoVE 56067

 JoVE Medicine

Assessment of Pulmonary Capillary Blood Volume, Membrane Diffusing Capacity, and Intrapulmonary Arteriovenous Anastomoses During Exercise

1,2, 3, 1,4, 1,2, 1,5

1Division of Pulmonary Medicine, University of Alberta, 2Faculty of Physical Education and Recreation, University of Alberta, 3Divisions of Critical Care and Cardiology, University of Alberta, 4Faculty of Rehabilitation Medicine, University of Alberta, 5G.F. MacDonald Centre for Lung Health


JoVE 54949

 JoVE Medicine

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

1, 3, 3, 2, 2, 2

1Department of Surgery, Interdisciplinary Consortium on Advanced Motion Performance (iCAMP), College of Medicine, University of Arizona, 2Department of Medicine, Division of Infectious Disease, College of Medicine, University of Arizona, 3Interdisciplinary Consortium on Advanced Motion Performance (iCAMP), Division of Vascular Surgery and Endovascular Therapy, Michael E. DeBakey Department of Surgery, Baylor College of Medicine


JoVE 54275

 Science Education: Essentials of Genetics

An Overview of Genetic Analysis

JoVE Science Education

An organism’s physical traits, or phenotype, are a product of its genotype, which is the combination of alleles (gene variants) inherited from its parents. To varying degrees, genes interact with each other and environmental factors to generate traits. The distribution of alleles and traits within a population is influenced by a number of factors, including natural selection, migration, and random genetic drift.In this video, JoVE introduces some of the foundational discoveries in genetics, from Gregor Mendel’s elucidation of the genetic basis of inheritance, to how natural processes affect allele distributions within populations, to the modern synthesis of biology that brought together Mendelian genetics and Darwinian evolution. We then review the questions asked by geneticists today regarding how genes influence traits, and some of the main tools used to answer these questions. Finally, several applications of techniques such as genetic crosses, screens and evolution experiments will be presented.…

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