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Interleukin-4: A soluble factor produced by activated T-Lymphocytes that induces the expression of Mhc class ii genes and Fc receptors on B-Lymphocytes and causes their proliferation and differentiation. It also acts on T-lymphocytes, Mast cells, and several other hematopoietic lineage cells.

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development

1Department of Internal Medicine, Division of Hematology and Oncology, University of California, Davis, 2Comparative Pathology Laboratory, UC Davis School of Veterinary Medicine, University of California, Davis, 3Merck Serono Research, Merck KGaA, Darmstadt, Germany

JoVE 50868


 Medicine

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