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Leukotriene C4: The conjugation product of Leukotriene a4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some Vascular smooth muscle. (From Dictionary of Prostaglandins and Related Compounds, 1990)
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