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Night Vision: Function of the human eye that is used in dim illumination (scotopic intensities) or at nighttime. Scotopic vision is performed by Retinal rod photoreceptors with high sensitivity to light and peak absorption wavelength at 507 nm near the blue end of the spectrum.

Vibratome Sectioning Mouse Retina to Prepare Photoreceptor Cultures

1Department of Genetics, UMR_S 968, Institut de la Vision, 2Department of Visual Information, UMR_S 968, Institut de la Vision, 3Exploratory Team, UMR_S 968, Institut de la Vision, 4Sorbonne Universités, Paris 06, UMR_S 968, Institut de la Vision, 5INSERM, U968, Institut de la Vision, 6CNRS, UMR_7210, Institut de la Vision

JoVE 51954


Recording Mouse Ultrasonic Vocalizations to Evaluate Social Communication

1Human Genetics and Cognitive Functions, University Paris Diderot, CNRS UMR 3571, Institut Pasteur, 2Neurophysiology and Behavior, University Pierre et Marie Curie Paris 6, CNRS UMR 7102, 3Bio Image Analysis, CNRS URA 2582, Institut Pasteur

JoVE 53871


Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina

1Institute for Ophthalmic Research, University of Tübingen, 2Graduate School of Cellular & Molecular Neuroscience, University of Tübingen, 3Bernstein Centre for Computational Neuroscience, University of Tübingen, 4Molecular Genetics Laboratory, University of Tübingen, 5Centre for Ophthalmology, University of Tübingen

JoVE 52588


Description of a Novel, Surgically Implanted Neuromodulatory Technique Known As Bilateral Epidural Prefrontal Cortical Stimulation (Epcs) for Treatment-Resistant Depression (TRD)

1Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 2Department of Neurosciences, Medical University of South Carolina, 3Ralph H. Johnson VA Medical Center, 4Department of Psychiatry and Behavioral Sciences, Stanford University, 5American University of Beirut Medical Center

Video Coming Soon

JoVE 56043

 JoVE In-Press

Transcriptomic Analysis of Human Retinal Surgical Specimens Using jouRNAl

1U968, Institut National de la Santé et de la Recherche Médicale, 2UMR S 968, Université Pierre et Marie Curie, 3UMR 7210, Centre National de la Recherche Scientifique, 4Départment d'Ophtalmologie, Centre Hospitalier Universitaire de Bordeaux

JoVE 50375


Photoelectric Effect

JoVE 10413

Source: Yong P. Chen, PhD, Department of Physics && Astronomy, College of Science, Purdue University, West Lafayette, IN

Photoelectric effect refers to the emission of electrons from a metalwhen light is shining on it. In order for the electrons to be liberated from the metal, the frequency of the light needs to be sufficiently high such that the photons in the light have sufficient energy. This energy is proportional to the light frequency.The photoelectric effect provided the experimental evidence for the quantum of light that is known as photon. This experiment will demonstrate the photoelectric effect using a charged zinc metal subject to either a regular lamp light, or ultraviolet (UV) light with higher frequency and photon energy.The zinc plate will be connected to an electroscope, an instrument that can read the presence and relative amount of charges. The experiment will demonstrate that the UV light, but not the regular lamp, can discharge the negatively charged zinc by ejecting its excess electrons.Neither light source, however, can discharge positively charged zinc, consistent with the fact that electrons that are emitted in photoelectric effect.

 Physics II

Physiological Correlates of Emotion Recognition

JoVE 10297

Source: Laboratories of Jonas T. Kaplan and Sarah I. Gimbel—University of Southern California

The autonomic nervous system (ANS) controls the activity of the body's internal organs and regulates changes in their activity depending on the current environment. The vagus nerve, which innervates many of the internal organs, is an important part of the system. When our brain senses danger, vagal tone is inhibited, leading to a set of changes in the body designed to make us more prepared to fight or flee; for example, our heart rate increases, our pupils dilate, and we breath more quickly. Conversely, when the vagal system is activated, these physiological responses are inhibited, leading to a calmer state. The vagus nerve, then, acts as a kind of "brake" on our arousal. One interesting consequence of this calmer state is that it tends to promote social interaction-when we are not tensed and afraid of our immediate environment we are instead receptive to interacting with others. Poor functioning of this regulatory mechanism, therefore, may be associated with difficulties in social behavior. One index of autonomic regulation is heart rate variability (HRV). HRV is a measure of how much the gap between one beat and the next varies over time. High HRV means there are continual fluctuations in the


Flat-floored Air-lifted Platform: A New Method for Combining Behavior with Microscopy or Electrophysiology on Awake Freely Moving Rodents

1Neuroscience Center, University of Helsinki, 2Neurotar LTD, 3A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 4Laboratory Animal Center, University of Helsinki

JoVE 51869


A Behavioral Assay for Mechanosensation of MARCM-based Clones in Drosophila melanogaster

1Department of Biology, College of the Holy Cross, 2School of Medicine, Georgetown University, 3Department of Biochemistry, Giesel School of Medicine, Dartmouth College, 4School of Medicine, Tufts University, 5Transgenomic Inc., 6Department of Molecular, Cell and Cancer Biology, UMass Medical School

JoVE 53537


Children's Reliance on Artist Intentions When Identifying Pictures

JoVE 10117

Source: Laboratories of Judith Danovitch and Nicholaus Noles—University of Louisville

Children are not the best artists. Sometimes it’s easy to pick out the characteristic triangular head, whiskers, and tail of a cat, but children often describe elaborate scenarios that they depict as a beautifully unrecognizable mess. Thus, given children’s questionable artistic talent, how do they know what their drawings, and the drawings of others, represent? One way children identify pictures is by relying on resemblance. If it looks like a cat, then it’s a cat. However, some pictures do not clearly resemble any real object. In this situation, children must use other means to figure out what the picture represents, including their understanding of what the person who created the picture intended it to represent. By their first birthday, children are sensitive to the intentions of other people. They know that people’s actions are driven by their goals, and they can infer a person’s intentions even if the goal-directed action is not successful (e.g., they understand a person struggling to turn a lid intends to open a jar, even if they never see them succeed in opening it). By about age 3, children can use this understanding of intention to guide their interpretation

 Developmental Psychology

Measuring Children's Trust in Testimony

JoVE 10130

Source: Laboratories of Judith Danovitch and Nicholaus Noles—University of Louisville

How does a person learn about the world around them? One way is through direct observation and exploration. However, not every piece of information can be observed firsthand. Instead, a person must often rely on other people as information sources. This is particularly true for children who have so many questions about the world around them, yet have limited means of accessing the answers. Thus, children must rely on other people to provide answers to their questions. There is a popular viewpoint that children are gullible and that they believe everything they hear. However, recent research has shown this is not the case. Children as young as age 3 evaluate what other people say and show selective trust in other people’s testimony. Children pay attention to and use their knowledge about an individual’s prior behavior and characteristics to judge whether that individual is a trustworthy informational source.   This video demonstrates how to measure children’s trust in testimony based on methods developed by Birch, Vauthier, and Bloom1 and Koenig, Clement, and Harris.2 

 Developmental Psychology

Categories and Inductive Inferences

JoVE 10109

Source: Laboratories of Nicholaus Noles and Judith Danovitch—University of Louisville

It might be possible for the human brain to keep track of each individual person, place, or thing encountered, but that would be a very inefficient use of time and cognitive resources. Instead, humans develop categories. Categories are mental representations of real things that can be used for a variety of purposes. For example, individuals can use the perceptual features of animals to place them into a given category. So, upon seeing a furry, four-legged, tail-wagging, barking animal, a person can determine that it is a dog. This is one of many examples where people use perceptual similarity to fit new experiences into their existing mental representations. However, category membership is much more than skin deep, especially for representations of animals. Frank Keil demonstrated this by using a simple, yet powerful technique that focused on the differences between natural kinds and artifacts. Natural kinds include animals and other living things, while artifacts consist largely of nonliving things, such as tables or gold bricks. In his study, Keil told children stories about natural kinds and artifacts that underwent transformations causing them to cross categorical boundaries. For example, he

 Developmental Psychology

Motion-induced Blindness

JoVE 10196

Source: Laboratory of Jonathan Flombaum—Johns Hopkins University

One thing becomes very salient after basic exposure to the science of visual perception and sensation: what people see is a creation of the brain. As a result people may fail to see things, see things that are not there, or see things in a distorted way.

To distinguish between physical reality and what people perceive, scientists use the term awareness to refer to what people perceive. To study awareness, vision scientists often rely on illusions-misperceptions that can reveal the ways that the brain constructs experience. In 2001, a group of researchers discovered a striking new illusion called motion-induced blindness that has become a powerful tool in the study of visual awareness.1 This video demonstrates typical stimuli and methods used to study awareness with motion-induced blindness.

 Sensation and Perception

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Vision Training Methods for Sports Concussion Mitigation and Management

1Neurology and Rehabilitative Medicine, University of Cincinnati, 2Division of Sports Medicine, Department of Orthopaedic Surgery, University of Cincinnati, 3Department of Athletics, University of Cincinnati, 4Department of Neurosurgery, University of Cincinnati, 5College of Education, Criminal Justice, and Human Services, University of Cincinnati, 6Division of Sports Medicine, Cincinnati Children's Hospital Medical Center

JoVE 52648


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