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Receptors, GABA: Cell-surface proteins that bind Gamma-aminobutyric acid with high affinity and trigger changes that influence the behavior of cells. Gaba-a receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. Gaba-b receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.
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