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Sodium Chloride: A ubiquitous sodium salt that is commonly used to season food. It plays an important biological role in maintaining the osmotic tension of blood and tissues. The Osmolar concentration this and other Salts accounts for Salinity which influences the types of organisms that live in an Environment.

Engineering 'Golden' Fluorescence by Selective Pressure Incorporation of Non-Canonical Amino Acids and Protein Analysis by Mass Spectrometry and Fluorescence

1Institute of Chemistry L 1, Department of Biocatalysis, Technical University of Berlin, 2Institute of Chemistry PC 14, Department of Bioenergetics, Technical University of Berlin, 3Institute of Chemistry TC 7, Department of Physical Chemistry/Molecular Material Sciences, Technical University of Berlin

Video Coming Soon

JoVE 57017


 JoVE In-Press

Measurement of Extracellular Ion Fluxes Using the Ion-selective Self-referencing Microelectrode Technique

1Department of Dermatology, Institute for Regenerative Cures, University of California, Davis, 2Departamento de Biologia, Centro de Biologia Molecular e Ambiental, Universidade do Minho, 3Department of Neurology and Center for Neuroscience, University of California, Davis Imaging of Dementia and Aging Laboratory, 4Department of Ophthalmology, Institute for Regenerative Cures, University of California, Davis

JoVE 52782


 Biology

Creating a Structurally Realistic Finite Element Geometric Model of a Cardiomyocyte to Study the Role of Cellular Architecture in Cardiomyocyte Systems Biology

1Cell Structure and Mechanobiology Group, Department of Biomedical Engineering, University of Melbourne, 2Systems Biology Laboratory, Melbourne School of Engineering, University of Melbourne, 3Department of Biomedical Engineering, University of Melbourne, 4Department of Engineering Science, University of Auckland, 5Advanced Microscopy Facility, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, 6School of Medicine, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, 7School of Mathematics and Statistics, Faculty of Science, University of Melbourne, 8ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, University of Melbourne, 9Living Systems Institute, University of Exeter

Video Coming Soon

JoVE 56817


 JoVE In-Press

Nucleophilic Substitution

JoVE 10465

Source: Vy M. Dong and Daniel Kim, Department of Chemistry, University of California, Irvine, CA

Nucleophilic substitution reactions are among the most fundamental topics covered in organic chemistry. A nucleophilic substitution reaction is one where a nucleophile (electron-rich Lewis base) replaces a leaving group from a carbon atom.

SN1 (S = Substitution, N = Nucleophilic, 1 = first-order kinetics) SN2 (S = Substitution, N = Nucleophilic, 2 = second-order kinetics) This video will help to visualize the subtle differences between an SN1 and SN2 reaction and what factors help to speed up each type of nucleophilic substitution reaction. The first section will focus on reactions that will help to better understand and learn about nucleophilic substitution reactions. The second section will focus on a real-world example of a substitution reaction.


 Organic Chemistry II

Synthesis of Thermogelling Poly(N-isopropylacrylamide)-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering

1Department of Chemical Engineering, Rowan University, 2Department of Biological Sciences, Rowan University, 3Department of Biomedical Engineering, Drexel University

JoVE 53704


 Bioengineering

Polyelectrolyte Complex for Heparin Binding Domain Osteogenic Growth Factor Delivery

1Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, 2Centre for Research in Medical Devices (CÚRAM), National University of Ireland Galway, 3Department of Bioengineering, Faculty of Engineering, National University of Singapore, 4Tissue Engineering Program, National University of Singapore, 5Department of Orthopaedic Surgery and the Orthopaedic Hospital Research Center, University of California, Los Angeles

JoVE 54202


 Bioengineering

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