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General Surgery: A specialty in which manual or operative procedures are used in the treatment of disease, injuries, or deformities.

Isolation of Endothelial Progenitor Cells from Healthy Volunteers and Their Migratory Potential Influenced by Serum Samples After Cardiac Surgery

1Department of Intensive Care Medicine, University Hospital Aachen, 2Institute of Biochemistry and Molecular Biology, University Hospital Aachen, 3Department of Radiology, German Cancer Research Center, 4Department of Thoracic and Cardiovascular Surgery, University Hospital Aachen, 5Department of Vascular Biology, Institute for Stroke and Dementia Research (ISD), Klinikum der Universität München, 6Deutsches Zentrum für Herz-/Kreislaufkrankheiten (DZHK), Munich Heart Alliance

JoVE 55192


 Medicine

Shunt Surgery, Right Heart Catheterization, and Vascular Morphometry in a Rat Model for Flow-induced Pulmonary Arterial Hypertension

1Center for Congenital Heart Diseases, Department of Pediatric Cardiology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, 2Research and Development Facility, University Medical Center Groningen, University of Groningen

JoVE 55065


 Medicine

Considerations for Rodent Surgery

JoVE 10285

Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN

The Guide for the Care and Use of Laboratory Animals1 dictates that rodent survival surgery be performed aseptically. Aseptic technique utilizes specific practices that minimize the contamination of the surgical site, including patient preparation, surgeon preparation, sterilization of instruments and other supplies, and the use of a clean and controlled environment. Presurgical planning, intraoperative monitoring, and postoperative care are essential for successful recovery of animals from survival surgeries.


 Lab Animal Research

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

1Department of Anesthesiology, Pain, and Palliative Medicine, Radboud University Medical Center, 2Mech-Sense, Department of Gastroenterology & Hepatology, Aalborg University Hospital, 3Medical Technology & Clinical Physics, Radboud University Medical Center

JoVE 56918


 Medicine

An Anesthesia, Surgery, and Harvest Method for the Evaluation of Transpedicular Screws Using an In Vivo Porcine Lumbar Spine Model

1Department of Orthopaedic Surgery, Chonbuk National University School of Medicine, Chonbuk National University Hospital, 2Department of Orthopaedic Surgery, University of Seonam College of Medicine, Presbyterian Medical Center, 3Wowanimal Hospital, 4Department of Emergency Medicine, Inje University Busan Paik Hospital

JoVE 55225


 Medicine

Discovering Middle Ear Anatomy by Transcanal Endoscopic Ear Surgery: A Dissection Manual

1Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, 2Department of Otorhinolaryngology, Head & Neck Surgery, University Hospital of Modena, 3Department of Otorhinolaryngology, Head & Neck Surgery, University Hospital of Verona, 4Artificial Hearing Research, Artorg Center for Biomedical Engineering, University of Bern

JoVE 56390


 Medicine

Stereotaxic Surgery for Excitotoxic Lesion of Specific Brain Areas in the Adult Rat

1Helen Wills Neuroscience Institute, University of California Berkeley, 2Office of Laboratory Animal Care, University of California Berkeley, 3McGovern Institute for Brain Research & The Department of Brain and Cognitive Science, Massachusetts Institute of Technology, 4Integrative Biology Department, University of California Berkeley

JoVE 4079


 Neuroscience

An Anatomical Study of Nerves at Risk During Minimally Invasive Hallux Valgus Surgery

1Laboratory of Arthroscopic and Surgical Anatomy. Department of Pathology and Experimental Therapeutics (Human Anatomy and Embryology Unit), University of Barcelona, 2Health Sciences Faculty of Manresa, University of Vic-Central University of Catalunya, 3Groupe de Recherche et d'Etude en Chirurgie Mini-Invasive du Pied, GRECMIP, 4Foot and Ankle Unit, Hospital Quirón Barcelona, 5Foot and Ankle Unit, Orthopedic and Trauma Surgery, Royal London Hospital, Barts Health NHS Trust, 6Department of Orthopedic Surgery, Foot and Ankle Unit, University of Minnesota

JoVE 56232


 Medicine

A Step by Step Protocol for Subretinal Surgery in Rabbits

1Department of Ophthalmology, University of Bonn, 2Department of Ophthalmology, National University of Singapore, 3Geuder AG, 4Department of Ophthalmology, University of Münster, 5Section on Epithelial and Retinal Physiology and Disease, National Eye Institute/National Institutes of Health, 6Surgical Retina Department, Singapore National Eye Centre

JoVE 53927


 Medicine

Rodent Stereotaxic Surgery

JoVE 5205

Stereotaxic (or stereotactic) surgery is a method used to manipulate the brain of living animals. This technique allows researchers to accurately target deep structures within the brain through the use of a stereotaxic atlas, which provides the 3D coordinates of each area with respect to anatomical landmarks on the skull. After the skull is exposed, anesthetized animals are mounted on a specialized instrument known as a stereotaxic frame, which enables the precise placement of experimental tools at the defined coordinates. Stereotaxic surgery is a versatile approach that can be used to generate lesions, manipulate gene expression, or deliver experimental agents to the brain.This video-article provides a general overview of the principles behind stereotaxic surgery, including instructions for using a stereotaxic atlas and the stereotaxic frame, and an introduction to reading the Vernier scale for measurement of probe movements. The subsequent discussion outlines the steps required to perform the surgical procedure. Lastly, a broad range of technical applications are presented, such as the insertion of electrical probes to measure brain activity and genetic manipulation of brain tissue.


 Neuroscience

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

1Department of Cardiovascular and Thoracic Surgery, Pitié Salpêtrière University Hospital, Assistance Publique, Hôpitaux de Paris (APHP), Institut de Cardiologie, 2Institute of Veterinary Physiology and Zurich Center for Integrative Human Physiology, University of Zurich, 3Herzzentrum Hirslanden, Klinik St Anna, 4Department of Radiology, Canton Hospital Lucerne, 5Department of Anesthesiology and Intensive Care Unit, Pitié Salpêtrière University Hospital, Assistance Publique, Hôpitaux de Paris (APHP), Institut de Cardiologie

JoVE 57323


 Medicine

Rodent Behavioral Testing to Assess Functional Deficits Caused by Microelectrode Implantation in the Rat Motor Cortex

1Advanced Platform Technology Center, Rehabilitation Research and Development, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, 2Department of Biomedical Engineering, Case Western Reserve University

Video Coming Soon

JoVE 57829


 JoVE In-Press

Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice

1l'Institut du Thorax, INSERM, CNRS, UNIV Nantes, 2CHU Nantes, Institut des Maladies de l'Appareil Digestif, INSERM U913, 3l'Institut du Thorax, INSERM, CNRS, UNIV Nantes, CHU Nantes, 4Service de Clinique Chirurgicale Digestive et Endocrinienne, CHU de Nantes

JoVE 54905


 Medicine

Near-infrared Navigation System for Real-time Visualization of Blood Flow in Vascular Grafts

1Department of Radiology, University of Missouri, 2Office of Animal Resources, University of Missouri, 3Bioengineering, University of Missouri, 4Biomedical Science, University of Missouri, 5Surgery - Division of Cardiothoracic Surgery, University of Missouri, 6MU-iCATS, University of Missouri, 7Medical Pharmacology and Physiology, University of Missouri

Video Coming Soon

JoVE 54927


 JoVE In-Press

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

1Centre for Innovative Cancer Research, Ottawa Hospital Research Institute, 2Department of Cellular and Molecular Medicine, University of Ottawa, 3Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 4Department of Neurosurgery, The Second Hospital of Shandong University, 5Department of Medical Laboratory Technology, University of Tabuk, 6Department of Surgery, Ottawa General Hospital

JoVE 51253


 Medicine

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