David L. Spector

Publications

• Single Oligonucleotide Capture of RNA And Temperature Elution Series ( ) for Identification of RNA-binding Proteins
  Bio-protocol. Dec, 2022  |   Pubmed ID: 36618090
• Testing for Phylogenetic Signal in Single-Cell RNA-Seq Data
  Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. Dec, 2022  |   Pubmed ID: 36475926
• Platr4 is an Early Embryonic LncRNA That Exerts Its Function Downstream on Cardiogenic Mesodermal Lineage Commitment
  Developmental Cell. Nov, 2022  |   Pubmed ID: 36347239
• Simultaneous Visualization of RNA Transcripts and Proteins in Whole-mount Mouse Preimplantation Embryos Using Single-molecule Fluorescence Hybridization and Immunofluorescence Microscopy
  Frontiers in Cell and Developmental Biology. 2022  |   Pubmed ID: 36268512
• Allele-specific Differential Regulation of Monoallelically Expressed Autosomal Genes in the Cardiac Lineage
  Nature Communications. Oct, 2022  |   Pubmed ID: 36216821
• Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics
  Cancer Research. Apr, 2022  |   Pubmed ID: 35180770
• Noncoding RNAs: Biology and Applications-a Keystone Symposia Report
  Annals of the New York Academy of Sciences. 12, 2021  |   Pubmed ID: 34791665
• Activating a Collaborative Innate-adaptive Immune Response to Control Metastasis
  Cancer Cell. 10, 2021  |   Pubmed ID: 34478639
• LncRNA Regulates Myc Translation in Hepatocellular Carcinoma Via Sequestering TIAR
  ELife. May, 2021  |   Pubmed ID: 34002693
• : a Long Non-coding RNA Involved in Breast Cancer Progression
  Molecular & Cellular Oncology. 2021  |   Pubmed ID: 33860086
• MaTAR25 LncRNA Regulates the Tensin1 Gene to Impact Breast Cancer Progression
  Nature Communications. Dec, 2020  |   Pubmed ID: 33353933
• Comprehensive Analysis of Structural Variants in Breast Cancer Genomes Using Single-molecule Sequencing
  Genome Research. Sep, 2020  |   Pubmed ID: 32887686
• Long Non-Coding RNA: Functional Implications
  Non-coding RNA. Jun, 2020  |   Pubmed ID: 32503170
• MALAT1 Long Non-coding RNA and Breast Cancer
  RNA Biology. Jun, 2019  |   Pubmed ID: 30874469
• POU2F3 is a Master Regulator of a Tuft Cell-like Variant of Small Cell Lung Cancer
  Genes & Development. 07, 2018  |   Pubmed ID: 29945888
• Therapeutic Targeting of Long Non-Coding RNAs in Cancer
  Trends in Molecular Medicine. Mar, 2018  |   Pubmed ID: 29449148
• Antisense Oligonucleotide-mediated Knockdown in Mammary Tumor Organoids
  Bio-protocol. Aug, 2017  |   Pubmed ID: 28932764
• A LncRNA Fine Tunes the Dynamics of a Cell State Transition Involving , and DNA Methylation
  ELife. Aug, 2017  |   Pubmed ID: 28820723
• Identification and Characterization of a Class of MALAT1-like Genomic Loci
  Cell Reports. May, 2017  |   Pubmed ID: 28538188
• Mammary Tumor-Associated RNAs Impact Tumor Cell Proliferation, Invasion, and Migration
  Cell Reports. Sep, 2016  |   Pubmed ID: 27681436
• Differentiation of Mammary Tumors and Reduction in Metastasis Upon Malat1 LncRNA Loss
  Genes & Development. Jan, 2016  |   Pubmed ID: 26701265
• Quantitative Analysis of Chromatin Interaction Changes Upon a 4.3 Mb Deletion at Mouse 4E2
  BMC Genomics. Nov, 2015  |   Pubmed ID: 26589460
• Regulation of the ESC Transcriptome by Nuclear Long Noncoding RNAs
  Genome Research. Sep, 2015  |   Pubmed ID: 26048247
• Transient Pairing of Homologous Oct4 Alleles Accompanies the Onset of Embryonic Stem Cell Differentiation
  Cell Stem Cell. Mar, 2015  |   Pubmed ID: 25748933
• Non-rigid Multi-frame Registration of Cell Nuclei in Live Cell Fluorescence Microscopy Image Data
  Medical Image Analysis. Jan, 2015  |   Pubmed ID: 25181702
• Random Monoallelic Expression: Regulating Gene Expression One Allele at a Time
  Trends in Genetics : TIG. Jun, 2014  |   Pubmed ID: 24780084
• Identification and Initial Functional Characterization of a Human Vascular Cell-enriched Long Noncoding RNA
  Arteriosclerosis, Thrombosis, and Vascular Biology. Jun, 2014  |   Pubmed ID: 24578380
• Random Monoallelic Gene Expression Increases Upon Embryonic Stem Cell Differentiation
  Developmental Cell. Feb, 2014  |   Pubmed ID: 24576421
• Long Non-coding RNAs: Modulators of Nuclear Structure and Function
  Current Opinion in Cell Biology. Feb, 2014  |   Pubmed ID: 24529241
• Multiple Structural Maintenance of Chromosome Complexes at Transcriptional Regulatory Elements
  Stem Cell Reports. 2013  |   Pubmed ID: 24286025
• Role of SWI/SNF in Acute Leukemia Maintenance and Enhancer-mediated Myc Regulation
  Genes & Development. Dec, 2013  |   Pubmed ID: 24285714
• Receptor-mediated Delivery of Engineered Nucleases for Genome Modification
  Nucleic Acids Research. Oct, 2013  |   Pubmed ID: 23956220
• Chromatin Meets Its Organizers
  Cell. Jun, 2013  |   Pubmed ID: 23746835
• Lamin A/C is Expressed in Pluripotent Mouse Embryonic Stem Cells
  Nucleus (Austin, Tex.). 2013  |   Pubmed ID: 23324457
• Chromatin Organization and Transcriptional Regulation
  Current Opinion in Genetics & Development. Apr, 2013  |   Pubmed ID: 23270812
• The Noncoding RNA MALAT1 is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells
  Cancer Research. Feb, 2013  |   Pubmed ID: 23243023
• The LncRNA Malat1 is Dispensable for Mouse Development but Its Transcription Plays a Cis-regulatory Role in the Adult
  Cell Reports. Jul, 2012  |   Pubmed ID: 22840402
• Gene Bookmarking Accelerates the Kinetics of Post-mitotic Transcriptional Re-activation
  Nature Cell Biology. Oct, 2011  |   Pubmed ID: 21983563
• Biogenesis and Function of Nuclear Bodies
  Trends in Genetics : TIG. Aug, 2011  |   Pubmed ID: 21680045
• Four Amino Acids Guide the Assembly or Disassembly of Arabidopsis Histone H3.3-containing Nucleosomes
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2011  |   Pubmed ID: 21670303
• Direct Visualization of the Co-transcriptional Assembly of a Nuclear Body by Noncoding RNAs
  Nature Cell Biology. Jan, 2011  |   Pubmed ID: 21170033
• Nuclear Speckles
  Cold Spring Harbor Perspectives in Biology. Feb, 2011  |   Pubmed ID: 20926517
• Nonrigid Registration of 2-D and 3-D Dynamic Cell Nuclei Images for Improved Classification of Subcellular Particle Motion
  IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society. Apr, 2011  |   Pubmed ID: 20840894
• Regulation of the Histone H4 Monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent Degradation During DNA Damage
  Molecular Cell. Nov, 2010  |   Pubmed ID: 21035370
• Nuclear Organization and Dynamics of 7SK RNA in Regulating Gene Expression
  Molecular Biology of the Cell. Dec, 2010  |   Pubmed ID: 20881057
• A Long Nuclear-retained Non-coding RNA Regulates Synaptogenesis by Modulating Gene Expression
  The EMBO Journal. Sep, 2010  |   Pubmed ID: 20729808
• Chromatin Dynamics
  Annual Review of Biophysics. 2010  |   Pubmed ID: 20462379
• The Life of an MRNA in Space and Time
  Journal of Cell Science. May, 2010  |   Pubmed ID: 20427315
• An Unexpected Ending: Noncanonical 3' End Processing Mechanisms
  RNA (New York, N.Y.). Feb, 2010  |   Pubmed ID: 20007330
• Long Noncoding RNAs: Functional Surprises from the RNA World
  Genes & Development. Jul, 2009  |   Pubmed ID: 19571179
• Nuclear Neighborhoods and Gene Expression
  Current Opinion in Genetics & Development. Apr, 2009  |   Pubmed ID: 19339170
• MEN Epsilon/beta Nuclear-retained Non-coding RNAs Are Up-regulated Upon Muscle Differentiation and Are Essential Components of Paraspeckles
  Genome Research. Mar, 2009  |   Pubmed ID: 19106332
• 3' End Processing of a Long Nuclear-retained Noncoding RNA Yields a TRNA-like Cytoplasmic RNA
  Cell. Nov, 2008  |   Pubmed ID: 19041754
• 53BP1 Promotes Non-homologous End Joining of Telomeres by Increasing Chromatin Mobility
  Nature. Nov, 2008  |   Pubmed ID: 18931659
• Live Cell Dynamics of Promyelocytic Leukemia Nuclear Bodies Upon Entry into and Exit from Mitosis
  Molecular Biology of the Cell. Jul, 2008  |   Pubmed ID: 18480407
• Chromatin Dynamics and Gene Positioning
  Cell. Mar, 2008  |   Pubmed ID: 18358806
• A Genetic Locus Targeted to the Nuclear Periphery in Living Cells Maintains Its Transcriptional Competence
  The Journal of Cell Biology. Jan, 2008  |   Pubmed ID: 18195101
• Identification of Nuclear Dicing Bodies Containing Proteins for MicroRNA Biogenesis in Living Arabidopsis Plants
  Current Biology : CB. May, 2007  |   Pubmed ID: 17442570
• Eukaryotic Regulatory RNAs: an Answer to the 'genome Complexity' Conundrum
  Genes & Development. Jan, 2007  |   Pubmed ID: 17210785
• SnapShot: Cellular Bodies
  Cell. Dec, 2006  |   Pubmed ID: 17129789
• PIAS1 Confers DNA-binding Specificity on the Msx1 Homeoprotein
  Genes & Development. Apr, 2006  |   Pubmed ID: 16600910
• Rapid, Diffusional Shuttling of Poly(A) RNA Between Nuclear Speckles and the Nucleoplasm
  Molecular Biology of the Cell. Mar, 2006  |   Pubmed ID: 16371503
• Differential Regulation of Strand-specific Transcripts from Arabidopsis Centromeric Satellite Repeats
  PLoS Genetics. Dec, 2005  |   Pubmed ID: 16389298
• Regulating Gene Expression Through RNA Nuclear Retention
  Cell. Oct, 2005  |   Pubmed ID: 16239143
• Centromere Positioning and Dynamics in Living Arabidopsis Plants
  Molecular Biology of the Cell. Dec, 2005  |   Pubmed ID: 16195344
• Hypophosphorylated SR Splicing Factors Transiently Localize Around Active Nucleolar Organizing Regions in Telophase Daughter Nuclei
  The Journal of Cell Biology. Oct, 2004  |   Pubmed ID: 15479736
• Stopping for FISH and Chips Along the Chromatin Fiber Superhighway
  Molecular Cell. Sep, 2004  |   Pubmed ID: 15383273
• Human Orc2 Localizes to Centrosomes, Centromeres and Heterochromatin During Chromosome Inheritance
  The EMBO Journal. Jul, 2004  |   Pubmed ID: 15215892
• Dynamics of Single MRNPs in Nuclei of Living Cells
  Science (New York, N.Y.). Jun, 2004  |   Pubmed ID: 15205532
• Proteomic Analysis of Interchromatin Granule Clusters
  Molecular Biology of the Cell. Aug, 2004  |   Pubmed ID: 15169873
• Spatial and Temporal Regulation of Condensins I and II in Mitotic Chromosome Assembly in Human Cells
  Molecular Biology of the Cell. Jul, 2004  |   Pubmed ID: 15146063
• "On the Move"ments of Nuclear Components in Living Cells
  Experimental Cell Research. May, 2004  |   Pubmed ID: 15120987
• Tissue-specific Expression and Dynamic Organization of SR Splicing Factors in Arabidopsis
  Molecular Biology of the Cell. Jun, 2004  |   Pubmed ID: 15034145
• From Silencing to Gene Expression: Real-time Analysis in Single Cells
  Cell. Mar, 2004  |   Pubmed ID: 15006351
• The Dynamics of Chromosome Organization and Gene Regulation
  Annual Review of Biochemistry. 2003  |   Pubmed ID: 14527325
• Rb-mediated Heterochromatin Formation and Silencing of E2F Target Genes During Cellular Senescence
  Cell. Jun, 2003  |   Pubmed ID: 12809602
• Nuclear Choreography: Interpretations from Living Cells
  Current Opinion in Cell Biology. Apr, 2003  |   Pubmed ID: 12648670
• Sequential Entry of Components of the Gene Expression Machinery into Daughter Nuclei
  Molecular Biology of the Cell. Mar, 2003  |   Pubmed ID: 12631722
• A Molecular Dissection of Nuclear Function. Conference on the Dynamic Nucleus: Questions and Implications
  EMBO Reports. Jan, 2003  |   Pubmed ID: 12524514
• Disassembly of Interchromatin Granule Clusters Alters the Coordination of Transcription and Pre-mRNA Splicing
  The Journal of Cell Biology. Feb, 2002  |   Pubmed ID: 11827980
• Metabolic-energy-dependent Movement of PML Bodies Within the Mammalian Cell Nucleus
  Nature Cell Biology. Feb, 2002  |   Pubmed ID: 11753375
• Quantitative Imaging of Pre-mRNA Splicing Factors in Living Cells
  Molecular Biology of the Cell. Feb, 2000  |   Pubmed ID: 10679003
• Nucleocytoplasmic Shuttling: a Novel in Vivo Property of Antisense Phosphorothioate Oligodeoxynucleotides
  Nucleic Acids Research. Jan, 2000  |   Pubmed ID: 10606658
• Serine Phosphorylation of SR Proteins is Required for Their Recruitment to Sites of Transcription in Vivo
  The Journal of Cell Biology. Oct, 1998  |   Pubmed ID: 9786943
• The Perinucleolar Compartment and Transcription
  The Journal of Cell Biology. Oct, 1998  |   Pubmed ID: 9763419
• Phosphorothioate Antisense Oligonucleotides Induce the Formation of Nuclear Bodies
  Molecular Biology of the Cell. May, 1998  |   Pubmed ID: 9571236
• Role of the Modular Domains of SR Proteins in Subnuclear Localization and Alternative Splicing Specificity
  The Journal of Cell Biology. Jul, 1997  |   Pubmed ID: 9230067
• The Dynamic Organization of the Perinucleolar Compartment in the Cell Nucleus
  The Journal of Cell Biology. Jun, 1997  |   Pubmed ID: 9166399