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Transdermal Measurement of Glomerular Filtration Rate in Mice

Transdermal Measurement of Glomerular Filtration Rate in Mice

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Transdermal Measurement of Glomerular Filtration Rate in Mice

Transdermal Measurement of Glomerular Filtration Rate in Mice

21,505 Views

•

07:25 min

•

October 21, 2018

DOI:

10.3791/58520-v

DOI:

10.3791/58520-v

•

07:25 min

October 21, 2018

•

49 Views

Lauren Scarfe^1,2, Daniel Schock-Kusch³, Lorenzo Ressel⁴, Jochen Friedemann³, Yury Shulhevich³, Patricia Murray², Bettina Wilm², Mark de Caestecker¹

¹Division of Nephrology, Department of Medicine,Vanderbilt University Medical Center, ²Department of Cellular and Molecular Physiology,University of Liverpool, ³MediBeacon GmbH, ⁴Department of Veterinary Pathology and Public Health, Institute of Veterinary Science,University of Liverpool

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Summary

Here we describe a protocol to measure glomerular filtration rate (GFR) in conscious, freely moving mice using a transdermal GFR monitor.

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