Dr Maria Vinci obtained her Master degree in Biology at the University of Bari, Italy, in 2002 and soon after she joined the laboratory of Professor Elisabetta Dejana, at IFOM in Milan, where she studied the role of junctional adhesion molecules in inflammation. In 2004 Maria moved to Mannheim, Germany, for her PhD studentship in Tumour Vascular Biology, at Ruprecht-Karls-University of Heidelberg, under the supervision of Professor Peter Vajkoczy. In 2008 she joined The Institute of Cancer Research (ICR) in Sutton, UK, as a PostDoc in the Tumour Biology and Metastasis team, led by Professor Sue Eccles, where she dedicated herself to the establishment of 3D tumour models to study in a more physiological manner the response to pharmacological treatments, in vitro. In 2012, still at the ICR, Maria moved to the Glioma team, led by Professor Chris Jones, where she started investigating some of the most aggressive pediatric brain tumours, glioblastomas (GBM) and diffuse intrinsic pontine gliomas (DIPG). Maria obtained specific funding to extend her research into the field of pGBM and DIPG, a field of research she is strongly committed and passionate about. Since 2017, Dr. Vinci is at the Bambino Gesù Children’s Hospital, in Rome, Italy, where she leads the Pediatric High-Grade Glioma group, focusing her research on the cellular and molecular mechanisms driving the infiltrative growth of these tumours, and aiming to identify new therapeutic approaches to inhibit them. The establishment and application of 3D cancer models is at the centre of her research interests.