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Methods Collections > Methods to study cancer cell phenotypes and drug efficacy in vitro and in vivo   

Giridhar Mudduluru

Affiliation: Children’s Research Institute, Children’s Mercy Kansas City, MO

Giridhar Mudduluru, Ph.D. is a Research Scientist at Children’s Research Institute, Children’s Mercy Kansas City, MO. He obtained his Ph.D.  in molecular oncology in solid cancer and translation metastasis research from Heidelberg University and German Cancer Research Center (DKFZ), Germany. Before his doctoral work, he worked as a bioinformatician (Ocimum Biosolutions) and as a senior research fellow at Indian Institute of Science (India), where he was actively involved in the development of data analyzing tools, LIMS system, and in determining the novel genes role in cancer metastasis and drug resistance. During his doctoral, postdoctoral and as junior group leader he continued his work in understanding the differences in cancer -gene regulation (epigenetic, transcriptional, post-transcriptional) -signaling axis, -drug resistance of molecules like Axl, uPAR, PDCD4, MACC1, S100A4, miR-34, miR-21, miR-200c and translation research.  At his present position, he is studying the key molecules mechanistic function in metastasis process and drug discovery. Specifically, determining and developing novel drugs to combat the metastasis spread and cancer.

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