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Methods Collections > Emerging Techniques for 3D Imaging in Neuroscience

Matheus de Castro Fonseca

Affiliation: Laboratório Nacional de Biociências

Dr. Matheus Fonseca is a researcher in the Brazilian Biosciences National Laboratory (LNBio) at the Brazilian Center for Research in Energy and Materials (CNPEM), Brazil. He is also a collaborator professor at the State University of Campinas (UNICAMP), Brazil. He graduated in Biological Sciences and concluded his Master's Degree in Cell Biology, focusing on image techniques used to study synaptic vesicle exocytosis at the mouse neuromuscular junction. He received his Ph.D. in Pharmacology and Physiology after studying the role of calcium signaling and cell proliferation induced by insulin. His entire career relied on the usage of several imaging techniques to study cell biology in vitro and in vivo. He has recently developed a technique used to image in 3D entire neural structures using synchrotron-based X-ray microtomography.

Currently, his research combines molecular, cellular and imaging approaches in order to study the mechanisms behind Idiopathic Parkinson’s Disease. In addition, he develops new imaging techniques in order to visualize whole organs with cellular and subcellular resolution in 3D using X-rays and microtomography.

 

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