Nathalie GIGLIOLI- GUIVARC'H, completed her PhD in 1995 of the University of Paris XI-Orsay under the supervision of Dr Jean Vidal from CNRS. She is now Professor at the University of Tours and Director of the Research laboratory of Biomolecules and Plant Biotechnology. Throughout her research career, Pr Nathalie GIGLIOLI- GUIVARC'H, focused on primary and specialized plant metabolisms and plant biotechnology. She has published more than 85 research articles and reviews in internationally renowned journals and edited a book on alkaloids. At present, she currently develops research projects aimed at studying the specialized metabolism of plants leading to the production of natural products with interests for pharmacology or cosmetics. Her work focuses on the elucidation of biosynthetic mechanisms of plant natural products (alkaloids in particular) and their exploitation by metabolic engineering approaches. She is coordinating research programs in collaboration with industrial compagnies and is involved in an European consortium on the bioproduction of plant anti-cancer compounds in a heterologous system such as yeast. She is also coordinating research programs on the production via plant cell cultures of active extracts for cosmetic applications. In this context, she is working with Dr Bilal Abbasi from Quaid-i-Azam University (Islamabad, Pakistan) and Dr Christophe Hano from University of Orléans (France) to explore the potential of Loire Valley Region flora for cosmetic applications. Her field of expertise also extends to phenolic compounds from the vine and biopesticides. Pr Nathalie GIGLIOLI-GUIVARC’H is currently Member of scientific council of the Cosmetic Valley network and a member of the National Council of the French Universities. She was visiting professor in the department of Plant biotechnology of the university of Antioquia, Medellin (Colombia), of the Anna University, Chennai (India) and Pharmaceutic faculty of Medicinal University of Samarra (Russia).