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Methods Collections > Cellular models of neurodegeneration  

Jacqueline Burré

Affiliation: Brain and Mind Research Institute, Weill Cornell Medicine

Jacqueline Burré, Ph.D. is an Assistant Professor of Neuroscience in the Feil Family Brain and Mind Research Institute at Weill Cornell Medicine. She obtained her Ph.D. in Biochemistry from Goethe University in Germany, where she studied the make-up of synaptic vesicles, small lipid-protein particles within neurons that mediate neuronal communication. As a post-doctoral fellow at Stanford University, she pursued her interests in neuronal communication, focusing on the role of alpha-synuclein in normal brain function and in Parkinson’s disease. In 2014, she established her own research program at Weill Cornell Medicine, where she aims to determine the molecular mechanisms underlying diseases such as Parkinson’s disease, Alzheimer’s disease, and varied encephalopathies linked to mutations in Munc18-1/STXBP1, with a focus on the neuronal synapse. Her work has provided key insights into the normal function of disease-linked proteins in the brain, as well as into how dysfunction of these proteins contributes to neuropathology and disease. Ultimately, her goal is to identify rescue strategies, to overcome the deficits associated with dysfunction of these disease-linked proteins and the accompanying brain pathology.

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