Trial ends in Request Full Access Tell Your Colleague About Jove

Methods Collections > Artificial oocyte activation to create parthenogenetic blastocysts.

Adriana Bos-Mikich

Affiliation: Federal University of Rio Grande do Sul

Dr. Adriana Bos-Mikich received her Ph.D. from the Experimental Embryology and Teratology Unit, Medical Research Council at the University of London (UK) in 1994. Her thesis mentor was Prof. Dr. David Whittingham and she described the chromosome complement of cryopreserved mouse oocytes after parthenogenetic activation. Her work involved different activation agents and intracellular Ca2+ measurements during activation. Dr. Bos-Mikich moved to the University of Aberdeen (Scotland, UK) for a clinical/research position in the Assisted Reproduction Unit, where she took part in a research project that involved the culture of triploid human embryos for the creation of human embryonic stem cell (hESC) lineages. Dr. Bos-Mikich joined the Federal University of Rio Grande do Sul (UFRGS, Brazil), in 2007 on a lecturer position. In 2008, she spent one year at Roslin Cells (Roslin, UK) working with parthenogenetic activation of human oocytes and derivation and culture of hESCs. At the UFRGS, she has been working with parthenogenetic activation of human and bovine oocytes to generate hESCs under clinical-grade conditions. Her present research interests include the use of chemically defined substrates for derivation and culture of stem cells and the effects of different activation strategies on cloning efficacy for the cattle industry.

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
simple hit counter