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Rabies is an acute progressive encephalitis caused by a lyssavirus. The case fatality of this zoonosis is the highest for any infectious disease. Although laboratory tech…
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Obesity has become a major worldwide public health issue, dramatically increasing the risk of developing cardiovascular disease, type 2 diabetes, and liver diseases. Obes…
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Rheumatoid arthritis (RA) is the most common acute-inflammatory autoimmune connective tissue arthropathy. The majority of experimental evidence based on genetics, tissue …
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Antimicrobial peptides (AMPs) are versatile and are produced by all life forms. AMPs have diverse bioactivities against various pathogens, including bacteria, fungi, and …
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The field of immunology has been continually enriched by a detailed study of its components and how they cross-regulate to generate a synchronized and durable immune resp…
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Our intestinal microbiome is essential for the development and immunological education of the local tissues or lymph nodes, including Peyer’s patches and mesenteric…
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The host response to viral infections is a critical determinant for severe disease pathogenesis. Interdisciplinary approaches such as omics technologies, high-throughput …
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Alphavirus, a genus of mosquito-borne arboviruses, cause endemic disease globally and are of serious public health concern. Arthritogenic alphaviruses such as Mayaro viru…
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Psoriasis is an immune-mediated chronic inflammatory disorder of the skin characterized by hyperproliferation and extensive differentiation of keratinocytes. It affects n…
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Brain ischemia occurs when the blood flow to the entire brain (global) or part of the brain (focal) is interrupted. In the cl…

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Programmed host cell death in response to danger signals, damage, or pathogen infection, is crucial for tissue homeostasis, innate immunity, and control of inflammatory r…
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Transboundary animal diseases (TAD) cause massive loss to the livestock industry every year leading to hunger, food insecurity, and causing huge economic impact in many c…
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Immunometabolism research can help us understand how immune cells react in different situations (e.g., infection, cancer, and autoimmunity). Although the study of cellula…
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In immunological terms, the mammalian digestive tract, ranging from oral mucosal surfaces through stomach, small intestine and ending in the colon, comprise tissue compar…
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Macrophages are diverse in their phenotypic markers, physiology, and biological role. Classically activated and alternatively activated macrophages are part of the range …
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Malaria continues to be a global health issue, with almost half of the globe's population living in areas at risk of infection. Globally, a reduction in the number of…
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Macrophages, also known as professional phagocytes, have been shown to play essential roles in a variety of functions such as development, homeostasis, tissue repair, and…
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The microbial world has been fascinating and its study over the years has opened new dimensions that has led to the discovery of micro-compartments within certain pathoge…
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The cornea is one of the most compactly innervated and sensitive tissues in the body. The ocular surface integrity is maintained by nerves arising from the ophthalmic bra…
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Vaccination is historically one of the most significant medical interventions to reduce fatality and morbidity by controlling and preventing diseases. Earlier conventiona…
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Research on the relationship between human microecology (gut flora, respiratory flora, vaginal flora, etc.) and infection immunity, especially respiratory flora and respi…
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We are observing an impressive progress in medical diagnostics and therapeutic systems in the last decades, due to the advancements in many fields of biology and medicine…
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Tuberculosis (TB) is one of the leading causes of mortality worldwide due to a single infectious agent. Approximately two billion people, that is a quarter of the world p…
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The innate immune system is crucial to defend against viruses or other pathogenic microbes in the early phases of infection. The response starts with detecting evolutiona…
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Diseases are the leading cause of death and most fatal diseases are associated with ageing. Model organisms are crucial to gain a better understanding of the nature of ag…
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Use of large animal models to answer important biological research questions is becoming increasingly more common. This is due, in part, to the ever-growing body of liter…
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Blood is an essential biological tissue that facilitates transport of oxygen and nutrients to metabolically active tissues while enabling the elimination of the waste pro…
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Tuberculosis (TB) is the major cause of morbidity and mortality in many countries. The increase in multidrug resistant (MDR) and XDR TB cases implies that more effective …
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Successfully establishing residence within a eukaryotic host cell is a challenge for bacteria, yet pathogens (e.g., Chlamydia, Coxiella, Legionella<…
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Acinetobacter baumannii is an opportunistic human pathogen that has been classified by the World Health Organization as the most prevalent clinical bacterium, in…
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Biomaterials play a significant role in tissue engineering. They are constructed in a way to provide architectural infrastructure reminiscent of native extracellular matr…
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Proteases belong to a class of enzymes that hydrolyze proteins, and they are vital to the physiology of living organisms. They have been well characterized to have an imp…
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