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Cancer stem cells (CSCs) drive tumors and are necessary for their maintenance and growth. Therefore, these CSCs must be identified and targeted for better therapeutic suc…
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While immunotherapies have revolutionized cancer treatment for various indications, reliable and reproducible pre-clinical modeling remains difficult. This is particularl…
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Gallbladder cancer (GBC) is highly aggressive and metastatic. The tumor microenvironment is emerging as an essential regulator of tumorigenesis at multiple levels in GBC.…
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Current management of primary and metastatic brain tumors represents a unique challenge with multiple resistance mechanisms that must be overcome. These include limited p…
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Despite rapid progress in the discovery of therapeutic drugs for cancer treatment, following standard chemotherapy, chances of recurrence are high, with tumor cells exhib…
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Metastasis is the primary cause of cancer-related deaths where malignant cells disseminate from the primary tumor, invade through the extracellular matrix and basement me…
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