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April 18, 2012
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Zebrafish represents a valuable model to study the mechanisms of heart regeneration in vertebrates. Here, we present a protocol for induction of a heart infarct in adult zebrafish using cryoinjury. This method results in massive cell death within 20% of the ventricular wall, similar to that observed in mammalian infarcts.
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Chablais, F., Jaźwińska, A. Induction of Myocardial Infarction in Adult Zebrafish Using Cryoinjury. J. Vis. Exp. (62), e3666, doi:10.3791/3666 (2012).
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