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Magnetic Tweezers for the Measurement of Twist and Torque
JoVE Journal
Bioinżynieria
This content is Free Access.
JoVE Journal Bioinżynieria
Magnetic Tweezers for the Measurement of Twist and Torque

Magnetic Tweezers for the Measurement of Twist and Torque

English

Automatycznie wygenerowane

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11:41 min

May 19, 2014

DOI:

11:41 min
May 19, 2014

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Podsumowanie

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Magnetic tweezers, a powerful single-molecule manipulation technique, can be adapted for the direct measurements of the twist (using a configuration called freely-orbiting magnetic tweezers) and torque (using a configuration termed magnetic torque tweezers) in biological macromolecules. Guidelines for performing such measurements are given, including applications to the study of DNA and associated nucleo-protein filaments.

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