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May 24, 2016
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This protocol describes a highly reproducible model of cardiac regeneration by surgical induction of myocardial infarction in the left ventricle of postnatal day 1 mice. The method involves induction of hypothermic anesthesia and ligation of the left anterior descending coronary artery.
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Blom, J. N., Lu, X., Arnold, P., Feng, Q. Myocardial Infarction in Neonatal Mice, A Model of Cardiac Regeneration. J. Vis. Exp. (111), e54100, doi:10.3791/54100 (2016).
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