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Chapter 1

General Pharmacological Principles

Chapter 1

General Pharmacological Principles

Drug Discovery: Overview
Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for …
Preclinical Development: Overview
Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. …
Clinical Trials: Overview
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific …
Drug Nomenclature
During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United …
Drug Regulation
Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. …
Drug Classes and Categories
Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that …
Drug-Receptor Bonds
Drug-receptor bonds are formed through various chemical forces when drugs interact with target cells. Covalent bonds, strong and irreversible, are …
Drug-Receptor Interactions
Drug-receptor interaction describes the binding of receptors by drugs, but not all drug-receptor interactions result in activation and tissue response. …
Routes of Drug Administration: Overview
Drug administration involves delivering drugs to the body through various routes, such as enteral, parenteral, and topical. Enteral administration refers …
Routes of Drug Administration: Enteral
Medications can be administered through the enteral route using liquids, capsules, or tablets. Enteral administration involves drug administration via the …
Routes of Drug Administration: Parenteral
The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability …
Additional Routes of Drug Administration
Choosing the appropriate route of drug administration is significantly influenced by two key factors: the therapeutic objectives and the inherent …
Prescription, Nonprescription and Orphan Drugs
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including …
Factors Affecting Drug Response: Overview
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily …