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August 03, 2015
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Here we present a reliable method to study adult kidney regeneration by inducing acute kidney injury by gentamicin injection. We show that injury is dependent on gentamicin dosage and environmental temperature using in situ hybridization to label lhx1a+ developing new nephrons.
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Kamei, C. N., Liu, Y., Drummond, I. A. Kidney Regeneration in Adult Zebrafish by Gentamicin Induced Injury. J. Vis. Exp. (102), e51912, doi:10.3791/51912 (2015).
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