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第11章
原核生物的转录衰减
Transcriptional attenuation occurs when RNA transcription is prematurely terminated due to the formation of a terminator mRNA hairpin…
核糖开关
Riboswitches are non-coding mRNA domains that regulate the transcription and translation of downstream genes without the help of proteins.…
RNA(核糖核酸)编辑
RNA editing is a post-transcriptional modification where a precursor mRNA (pre-mRNA) nucleotide sequence is changed by base insertion, deletion, or…
调控的mRNA(信使核糖核酸)转运
In eukaryotes, transcription and translation are compartmentalized; an mRNA is first synthesized in the nucleus and then selectively transported to…
泄漏扫描
During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start…
mRNA(信使核糖核酸)稳定性和基因表达
The structure and stability of mRNA molecules regulates gene expression, as mRNAs are a key step in the pathway from gene to protein. In eukaryotes,…
RNA 干扰
RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the expression of a gene by binding to its messenger RNA (mRNA)…
微核糖核酸
MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of…
siRNA - 小分子干扰核糖核酸
Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional…
piRNA-Piwi(微小)相互作用核糖核酸
PIWI-interacting RNAs, or piRNAs, are the most abundant short non-coding RNAs. More than 20,000 genes have been found in humans that code for piRNAs…
CRISPR(核酸剪刀)和crRNA
Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to…
lncRNA - 长链非编码核糖核酸
In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces…
核酶
The term ribozyme is used for RNA that can act as an enzyme. Ribozymes are mainly found in selected viruses, bacteria, plant organelles, and lower…
早期地球的条件
Around 4 billion years ago, oceans began to condense on earth while volcanic eruptions released nitrogen, carbon dioxide, methane, ammonia, and…
合并绝对和相对定量PCR数据来量化STAT3剪接变体成绩单
Human signal transducer and activator of transcription 3 (STAT3) is one of many genes containing a tandem splicing site. Alternative donor splice…
有效转录控制质粒表达系统,用于研究原发性奥子拉皮细胞中mRNA笔录稳定性
Studying posttranscriptional regulation is fundamental to understanding the modulation of a given messenger RNA (mRNA) and its impact on cell…
水生甲壳虫中的RNA干扰是特定发育时间点操纵基因表达的有力工具
RNA interference (RNAi) remains a powerful technique that allows for the targeted reduction of gene expression through mRNA degradation. This…

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