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Bölüm 11
Prokaryotlarda Transkripsiyon Zayıflaması
Transcriptional attenuation occurs when RNA transcription is prematurely terminated due to the formation of a terminator mRNA hairpin…
Riboanahtarlar
Riboswitches are non-coding mRNA domains that regulate the transcription and translation of downstream genes without the help of proteins.…
RNA Düzeltimi
RNA editing is a post-transcriptional modification where a precursor mRNA (pre-mRNA) nucleotide sequence is changed by base insertion, deletion, or…
Regüle mRNA Transportu
In eukaryotes, transcription and translation are compartmentalized; an mRNA is first synthesized in the nucleus and then selectively transported to…
Sızdıran Tarama
During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start…
mRNA Stabilitesi ve Gen Ekspresyonu
The structure and stability of mRNA molecules regulates gene expression, as mRNAs are a key step in the pathway from gene to protein. In eukaryotes,…
RNA Girişimi
RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the expression of a gene by binding to its messenger RNA (mRNA)…
MikroRNA’lar
MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of…
siRNA - Küçük İnterferans RNA'lar
Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional…
piRNA - Piwi etkileşimli RNA'lar
PIWI-interacting RNAs, or piRNAs, are the most abundant short non-coding RNAs. More than 20,000 genes have been found in humans that code for piRNAs…
CRISPR ve crRNA'lar
Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to…
lncRNA - Uzun Kodlamayan RNA'lar
In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces…
Ribozimler
The term ribozyme is used for RNA that can act as an enzyme. Ribozymes are mainly found in selected viruses, bacteria, plant organelles, and lower…
Erken Dünyadaki Koşullar
Around 4 billion years ago, oceans began to condense on earth while volcanic eruptions released nitrogen, carbon dioxide, methane, ammonia, and…
Mutlak ve Bağıl Kantitatif PCR Veri birleştirme STAT3 Splice Varyant Dökümünü belirlememize
Human signal transducer and activator of transcription 3 (STAT3) is one of many genes containing a tandem splicing site. Alternative donor splice…
Primer Alveolar Epitel Hücrelerde MRNA Transkriptlerinin Kararlılığının Araştırılması için Etkili Transkripsiyonel Kontrollü Plazmid Ekspresyon Sistemi
Studying posttranscriptional regulation is fundamental to understanding the modulation of a given messenger RNA (mRNA) and its impact on cell…
Belirli Gelişimsel Zaman Noktalarında Gen İfadesi Manipüle Etmek Için Güçlü Bir Araç Olarak Su Böcekleri RNA Girişim
RNA interference (RNAi) remains a powerful technique that allows for the targeted reduction of gene expression through mRNA degradation. This…

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