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מהו ביוטי גנים?
Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression…
הדוגמה המרכזית
The central dogma of biology states that information encoded in the DNA is transferred to messenger RNA (mRNA), which then directs the synthesis of…
גורמי שעתוק
Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component…
מבנה רנ״א
The basic structure of RNA consists of a five-carbon sugar and one of four nitrogenous bases. Although most RNA is single-stranded, it can form…
יציבות רנ״א
Intact DNA strands can be found in fossils, while scientists sometimes struggle to keep RNA intact under laboratory conditions. The structural…
עיבוד טרום-רנ״א שליח
In eukaryotic cells, transcripts made by RNA polymerase are modified and processed before exiting the nucleus. Unprocessed RNA is called precursor…
סוגים של רנ״א
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform…
מיקרו-רנ״א
MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of…
שחבור רנ״א
The process in which eukaryotic RNA is edited prior to protein translation is called splicing. It removes regions that do not code for proteins and…
בקרה אפיגנטית
Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases…
הפרעת רנ״א
RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the expression of a gene by binding to its messenger RNA (mRNA)…
אופרונים
Prokaryotes can control gene expression through operons—DNA sequences consisting of regulatory elements and clustered, functionally related…
כימות של מידע מקודד על ידי גנים ביטוי רמות במהלך תוחלת החיים אפנון תחת הגבלת תזונה מגוון רחב <em>C</em> . elegans
Sensory systems allow animals to detect, process, and respond to their environment. Food abundance is an environmental cue that has profound effects…
תאים יחידים Gene Expression Profiling שימוש FACS ו qPCR עם סטנדרטים פנימיים
Gene expression measurements from bulk populations of cells can obscure the considerable transcriptomic variation of individual cells within those…
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