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免疫系とは?
The immune system comprises diverse biological structures and processes that protect the body from disease. These processes can be classified into…
細胞を介した免疫反応
The cell-mediated immune system is the host’s primary response against invasive bacteria and viruses that cause intracellular infections. It…
体液性免疫応答
The humoral immune response, also known as the antibody-mediated immune response, targets pathogens circulating in “humors,” or…
抗体の構造
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by…
アフィニティとアビディティ
Antibodies bind to toxins or substances on the surface of cells, bacteria, viruses, or fungi. The substance is called an antigen, and the precise…
交差反応性
The ability of a single antibody to recognize multiple structurally similar epitopes is an important immune defense strategy that enables the host…
アレルギー性の反応
We speak of an allergy when the immune system triggers a response against a benign foreign structure, like food, pollen or pet dander. These…
炎症
In response to tissue injury and infection, mast cells initiate inflammation. Mast cells release chemicals that increase the permeability of…
ワクチン接種
Vaccination is the administration of antigenic material from pathogens to confer immunity against a specific microorganism. Vaccination primes the…
II-45同系ラット中皮腫モデルにおける同所移植と末梢免疫細胞の監視
The enormous upsurge of interest in immune-based treatments for cancer such as vaccines and immune checkpoint inhibitors, and increased understanding…
自己免疫性脱髄に薬理学的介入のためのCNS保護に対する免疫系の抑制を決定します
A major hallmark of the autoimmune demyelinating disease multiple sclerosis (MS) is immune cell infiltration into the brain and spinal cord resulting…
幼虫ゼブラフィッシュスキンにおける誘導GAL4 / UASの発現系を用いて自然免疫と前癌細胞の相互作用のライブイメージング
Here we describe a method to conditionally induce epithelial cell transformation by the use of the 4-Hydroxytamoxifen (4-OHT) inducible…
リポ多糖の腸粘膜バリアー違反の後微生物由来製品の入り口を模倣するマウスに注射
The intestinal epithelial barrier separates the host from the microbiota that is normally tolerated or ignored. The breach of this barrier results in…

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