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Cerebrum: Derived from Telencephalon, cerebrum is composed of a right and a left hemisphere. Each contains an outer cerebral cortex and a subcortical basal ganglia. The cerebrum includes all parts within the skull except the Medulla oblongata, the Pons, and the Cerebellum. Cerebral functions include sensorimotor, emotional, and intellectual activities.

What is a Nervous System?

JoVE 10838

The nervous system is the collection of specialized cells responsible for maintaining an organism’s internal environment and coordinating the interaction of an organism with the external world—from the control of essential functions such as heart rate and breathing to the movement needed to escape danger.

The vertebrate nervous system is divided into two major parts: the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS includes the brain, spinal cord, and retina—the sensory tissue of the visual system. The PNS contains the sensory receptor cells for all of the other sensory systems—such as the touch receptors in the skin—as well as the nerves that carry information between the CNS and the rest of the body. Additionally, part of both the CNS and PNS contribute to the autonomic nervous system (also known as the visceral motor system). The autonomic nervous system controls smooth muscles, cardiac muscles, and glands that govern involuntary actions, such as digestion. The vertebrate brain is primarily divided into the cerebrum, cerebellum, and brainstem. The cerebrum is the largest, most anterior part of the brain that is divided into left and right hemispheres. Each hemisphere is further divided into four lobes: frontal, parietal, occipital, and temporal. The outermost layer of the cerebrum is called

 Core: Biology

In Situ Detection of Autoreactive CD4 T Cells in Brain and Heart Using Major Histocompatibility Complex Class II Dextramers

1School of Veterinary Medicine and Biomedical Sciences, University of Nebraska, Lincoln, 2Center for Biotechnology, University of Nebraska, Lincoln, 3Nebraska Center for Virology and School of Biological Sciences, University of Nebraska, Lincoln

JoVE 51679

 Immunology and Infection

Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study

1Department of Neurology, Mayo Clinic, 2Mayo Clinic Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic, 3Center for Regenerative Medicine, Neuroregeneration, Mayo Clinic, 4Division of Neonatal Medicine, Mayo Clinic, 5Department of Pediatric and Adolescent Medicine, Mayo Clinic

JoVE 54139

 Immunology and Infection

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

1Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, 2Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, 3Mellen Center for Treatment and Research in Multiple Sclerosis, Neurological Institute, Cleveland Clinic

JoVE 59511

 Neuroscience
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