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Complement Membrane Attack Complex: A product of Complement activation cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target Cell membrane and cell lysis. It is formed by the sequential assembly of terminal complement components (Complement c5b; Complement c6; Complement c7; Complement c8; and Complement c9) into the target membrane. The resultant C5b-8-poly-C9 is the "membrane attack complex" or Mac.

Open Tracheostomy Gastric Acid Aspiration Murine Model of Acute Lung Injury Results in Maximal Acute Nonlethal Lung Injury

1Department of Anesthesiology, University at Buffalo, State University of New York, 2Department of Anesthsiology, Veterans Admistration Western New York Healthcare System, 3Institute of Lasers, Photonics and Biophotonics, University at Buffalo, State University of New York

JoVE 54700

 Medicine
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