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Genetics: The branch of science concerned with the means and consequences of transmission and generation of the components of biological inheritance. (Stedman, 26th ed)

What is Population Genetics?

JoVE 10962

A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool. While some alleles of a given gene might be observed commonly, other variants may be encountered at a much lower frequency. Gene pools are not static. The frequency and occurrence of alleles in a gene pool may change over time. For instance, allele frequencies change due to random mutations, natural selection, migration, and chance. Population genetics examines genetic variation within and between populations, and changes in allele frequencies across generations. Population geneticists use mathematical models to investigate and predict allele frequencies in populations. The gene pools of natural populations may vary significantly. One goal of population genetics is to determine genetic variation among different populations of the same species. Studying such variations has implications for species health, domestication, management and conservation. For instance, increased urbanization gradually fragments natural landscapes and leads to h

 Core: Biology

Genetics of Organisms- Concept

JoVE 10557

Mendelian Genetics

Evolution is caused by changes in the genetic composition of populations. In the field of population genetics, scientists model this process as changes in the frequency of alleles at individual genetic loci. This simple representation of how evolution occurs dates to Gregor Mendel’s analysis of trait inheritance patterns in pea plants, first presented in 1865.…

 Lab Bio

An Overview of Genetics and Disease

JoVE 5543

Many human diseases are associated with mutations or variations in genetic sequences. Some of these genetic variants are heritable, passed down from generation to generation, while others arise sporadically during an organism’s life and cause diseases such as cancer. Researchers are trying to identify and characterize these genetic alterations in the hopes of…


Genetics of Organisms - Prep Student

JoVE 10619

REF and WEF Fly Genetics
To prepare for the experiment, be sure to obtain cultures of Drosophila melanogaster at least two weeks ahead of the planned experiment day. NOTE: Because adult females store sperm after mating, you will need this time to generate virgin females by breeding the flies.
You should get two stock cultures: wildtype,…

 Lab Bio

Genetics of Organisms - Student Protocol

JoVE 10558

REF and WEF Fly Genetics
NOTE: At your station, you should have four vials of flies. They will be labeled as male or female. They will also be labeled with the notation REF for red-eyed flies or WEF for white-eyed flies. The female vial should also be labeled virgin as these flies should be unmated for the purpose of this experiment.
Make sure you …

 Lab Bio

An Introduction to Developmental Genetics

JoVE 5325

Development is the complex process through which a single-celled embryo transforms into a multicellular organism. Developmental processes are guided by information encoded in an organism's DNA, and geneticists are trying to understand how this information leads to a fully formed organism.

This video reviews seminal research in the field of developmental biology, including the…

 Developmental Biology
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