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Biology

OLE Isacson:帕金森氏病的新疗法的发展

doi: 10.3791/189 Published: April 29, 2007

Summary

OLE Isacson给出了一个简洁的概述,对帕金森病的原因,治疗策略,以及帕金森病研究的进展。

References

  1. Chung, C. Y., Seo, H., Sonntag, K. C., Brooks, A., Lin, L., Iasacson, O. Cell type specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability. Hum. Mol. Genet. 14, 1709-1725 (2005).
  2. Mendez, I., Sanchez-Pernaute, R., Cooper, O., Vinuela, A., Ferrari, D., Bjoerklund, L., Dagher, A., Isacson, O. Cell type analysis of fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease. Brain. 128, (7), 1498-1510 (2005).
  3. Cooper, O., Isacson, O. Intrastiatal Transforming Growth Factor Delivery to a Model of Parkinson's Disease Induces Proliferation and Migration of Endogenous Adult Neural Progenitor Cells without Differentiation into Dopaminergic Neurons. J. Neurosci. 24, (41), 8924-8931 (2004).
  4. Sanchez-Pernaute, R., Ferree, A., Cooper, O., Yu, M., Brownell, A. L., Isacson, O. Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat mod of Parkinson's disease. Journal of Neuroinflammation. (2004).
  5. Isacson, O. The production and use of cells as therapeutic agents in neurodegenerative diseases. Lancet Neurology. 2, (7), 417-424 (2003).
OLE Isacson:帕金森氏病的新疗法的发展
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Isacson, O. Ole Isacson: Development of New Therapies for Parkinson's Disease. J. Vis. Exp. (3), e189, doi:10.3791/189 (2007).More

Isacson, O. Ole Isacson: Development of New Therapies for Parkinson's Disease. J. Vis. Exp. (3), e189, doi:10.3791/189 (2007).

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