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Biology

Kvantificering Blanding med Magnetic Resonance Imaging

Published: January 25, 2012 doi: 10.3791/3493

Summary

Magnetic resonance imaging (MRI) giver et kraftfuldt værktøj til at evaluere effektiviteten af ​​procesudstyr under drift. Vi diskuterer brugen af ​​MRI til at visualisere blanding i en statisk mixer. Ansøgningen er relevant for produkter til personlig pleje, men kan anvendes til en bred vifte af fødevarer, kemisk, biomasse og biologiske væsker.

Abstract

Protocol

Discussion

Disclosures

Forfatter M. McCarthy er en konsulent til Aspect Imaging, Ltd Forfattere L. Bacca og W. Hartt er ansatte i Procter & Gamble Co

Acknowledgments

Forfatterne vil gerne takke Aspect Imaging (Industrial Area Hevel Modi'in, Shoham, Israel) for de benyttede puls-sekvenser i undersøgelsen. Dette arbejde blev delvist finansieret af en pris fra Center for Proces Analytisk Kemi ved University of Washington (Seattle, WA, USA), samt bidrag i naturalier og økonomisk støtte fra Procter & Gamble Company.

Materials

Name Company Catalog Number Comments
Aspect 1T imaging spectrometer Aspect Imaging
AR-G2 rheometer TA Instruments
Seepex metering pumps Seepex GmbH
Carbopol The Lubrizol corporation, (Wickliffe, OH)
Manganese Chloride 1M Solution Fisher Scientific

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References

  1. Callaghan, P. T. Principles of Nuclear Magnetic Resonance Microscopy. , Clarendon Press. Oxford. (1991).
  2. McCarthy, M. J. Magnetic Resonance Imaging in Foods. , Chapman & Hall. New York, NY. (1994).
  3. Mixer. US patent. Sluijters, R. , 3182965 (1965).
  4. van der Hoeven, J. C., Wimberger-Friedl, R., Meijer, H. E. H. Homogeneity of multilayers produced with a static mixer. Polymer. Eng. Sci. 41, 32-42 (2001).
  5. Steffe, J. F. Rheological Methods in Food Process Engineering. , 2nd Ed, Freeman Press. East Lansing, MI. (1996).
  6. Lee, Y., McCarthy, M. J., McCarthy, K. L. Extent of mixing in a two-component batch system measured using MRI. J. Food. Eng. 50, 167-174 (2001).
  7. McCarthy, K. L., Lee, Y., Green, J., McCarthy, M. J. Magnetic resonance imaging as a sensor system for multiphase mixing. Applied Magnetic Resonance. 22, 213-222 (2002).
  8. Choi, Y. J., McCarthy, M. J., McCarthy, K. L. MRI for process analysis: Co-rotating twin screw extruder. Journal of Process Analytical Chemistry. 9, 72-84 (2004).
  9. Rees, A. C., Davidson, J. F., Dennis, J. S., Fennell, P. S., Gladden, L. F., Hayhurst, A. N., Mantle, M. D., Muller, C. R., Sederman, A. J. The nature of the flow just above the perforated plate distributor of a gas-fluidised bed, as imaged using magnetic resonance. Chemical Eng. Sci. 61, 6002-6015 (2006).
  10. Stevenson, R., Harrison, S. T. L., Mantle, M. D., Sederman, A. J., Moraczewski, T. L., Johns, M. L. Analysis of partial suspension in stirred mixing cells using both MRI and ERT. Chem. Eng. Sci. 65, 1385-1393 (2010).
  11. Benson, M. J., Elkins, C. J., Mobley, P. D., Alley, M. T., Eaton, J. K. Three-dimensional concentration field measurements in a mixing layer using magnetic resonance imaging. Exp. Fluids. 49, 43-55 (2010).

Tags

Biofysik magnetisk resonans MRI blanding reologi statisk mixer split-og-rekombinere mix
Kvantificering Blanding med Magnetic Resonance Imaging
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Cite this Article

Tozzi, E. J., McCarthy, K. L.,More

Tozzi, E. J., McCarthy, K. L., Bacca, L. A., Hartt, W. H., McCarthy, M. J. Quantifying Mixing using Magnetic Resonance Imaging. J. Vis. Exp. (59), e3493, doi:10.3791/3493 (2012).

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