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Behavior

Gebruik van een acht-arm Radial Water Maze te Werken en Reference geheugen Assess Na Neonatale Hersenletsel

Published: December 4, 2013 doi: 10.3791/50940

Materials

Name Company Catalog Number Comments
Plastic Tub Gototanks http://www.gototanks.com ARM-19455 Size can vary depending on species tested or individual lab needs.
iPad or other digital tablet Apple Inc. N/A http://www.apple.com
Notability or other note taking application Gingerlabs N/A

http://www.gingerlabs.com

Digital pdf writer or notetaking program

Digital timer Any N/A
Deltaphase isothermal heating pad Braintree Scientific ASS7D http://www.braintreesci.com/
Stainless steel maze Fabricated in house N/A

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References

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  5. Hyde, L. A., Hoplight, B. J., Denenberg, V. H. Water version of the radial-arm maze: learning in three inbred strains of mice. Brain Res. 785 (2), 236-244 (1998).
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  7. Hyde, H. A., Hoplight, L. A., Denenberg, B. J., H, V. In two species, females exhibit superior working memory and inferior reference memory on the water radial-arm maze. Physiol. Behav. 70 (3-4), 311-317 (2000).
  8. Fitch, R. H., Breslawski, H., Rosen, G. D., Chrobak, J. J. Persistent spatial working memory deficits in rats with bilateral cortical microgyria. Behav. Brain Funct. 4, 45 (2008).
  9. Szalkowski, C. E., et al. Persistent spatial working memory deficits in rats following in utero RNAi of Dyx1c1. Genes Brain Behav. 10 (2), 244-252 (2011).
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  13. McClure, M. M., Thrlekeld, S. W., Fitch, R. H. The effects of erythropoietin on auditory processing following neonatal hypoxic-ischemic injury. Brain Res. 1132 (1), 203-209 (2007).
  14. LaPrairie, J. L., Murphy, A. Z. Long-term impact of neonatal injury in male and female rats: Sex differences, mechanisms and clinical implications. Front. Neuroendocrinol. 31 (2), 193-202 (2010).
  15. Volpe, J. J. Perinatal brain injury: from pathogenesis to neuroprotection. Ment. Retard. Dev. Disabil. Res. Rev. 7, 56-64 (2001).
  16. Vannucci, R. C., Vannucci, S. J. A model of perinatal hypoxic-ischemic brain damage. Ann. N. Y. Acad. Sci. 835, 234-249 (1997).
  17. McClure, M. M., Peiffer, A. M., Rosen, G. D., Fitch, R. H. Auditory processing deficits in rats with neonatal hypoxic-ischemic injury. Int. J. Dev. Neurosci. 23 (4), 351-362 (2005).
  18. Jarrard, L., Okaichi, H., Steward, O., Goldschmidt, R. On the role of hippocampal connections in the performance of place and cue tasks: comparisons with damage to the hippocampus. Behav. Neurosci. 98, 946-954 (1984).
  19. Bimonte-Nelson, H. A., et al. Testosterone, but not nonaromatizable dihydrotestosterone, improves working memory and alters nerve growth factor levels in aged male rats. Exp. Neurology. 181, 301-312 (2003).
  20. Acosta, J. I., Hiroi, R., Camp, B. W., Talboom, J. S., Bimonte-Nelson, H. A. An update on the cognitive impact of clinically-used hormone therapies in the female rat: Models, mazes and mechanisms. Brain Res. 13 (1514), 18-39 (2013).
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  22. Whishaw, I. Q., Pasztor, T. J. Rats alternate on a dry-land but not swimming-pool (Morris task) place task: implications for spatial processing. Behav. Neurosci. 114 (2), 442-446 (2000).
Gebruik van een acht-arm Radial Water Maze te Werken en Reference geheugen Assess Na Neonatale Hersenletsel
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Cite this Article

Penley, S. C., Gaudet, C. M.,More

Penley, S. C., Gaudet, C. M., Threlkeld, S. W. Use of an Eight-arm Radial Water Maze to Assess Working and Reference Memory Following Neonatal Brain Injury. J. Vis. Exp. (82), e50940, doi:10.3791/50940 (2013).

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