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Optical Recording of Electrical Activity in Guinea-pig Enteric Networks using Voltage-sensitive Dyes
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Optical Recording of Electrical Activity in Guinea-pig Enteric Networks using Voltage-sensitive Dyes

Article DOI: 10.3791/1631-v • 14:23 min • December 4th, 2009
December 4th, 2009 •
1, 1,2
1Department of Neuroscience, University of Pennsylvania-School of Medicine, 2Department of Physiology, University of Pennsylvania-School of Medicine

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This protocol illustrates how voltage-sensitive dyes enable optical recording of electrical activity from intact neural networks such as the plexuses of the guinea-pig enteric nervous system, with an adjustable resolution that ranges from single-cells to multi-ganglionic circuitry.

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Optical Recording Electrical Activity Guinea-pig Enteric Networks Voltage-sensitive Dyes Enteric Nervous System Myenteric Plexus Submucous Plexus Reflex Pathways Ganglia Synaptic Interactions Gastrointestinal Function Experimental Model Molecular Events Cellular Events Neuronal Network Physiological Outputs
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