Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Biology / Hi-C: En metod för att studera den…
JoVE Journal
Biology

This content is Open Access.

Mouse Genome Engineering Using Designer Nucleases
Journal (Biology)
Mouse Genome Engineering Using Designer Nucleases
Live-Cell Imaging of the Life Cycle of Bacterial Predator Bdellovibrio bacteriovorus using Time-Lapse Fluorescence Microscopy
Journal (Biology)
Live-Cell Imaging of the Life Cycle of Bacterial Predator Bdellovibrio bacteriovorus using Time-Lapse Fluorescence Microscopy
 
Click here for the English version

Hi-C: En metod för att studera den tredimensionella arkitektur för ledare.

Article DOI: 10.3791/1869-v • 22:27 min • May 6th, 2010
May 6th, 2010 •
*1, *2,3,4,5, *2, 6, 2, 3,6, 1, 2,7,8
1Program in Gene Function and Expression, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 2Broad Institute of Harvard and Massachusetts Institute of Technology, 3Division of Health Sciences and Technology, Massachusetts Institute of Technology, 4Program for Evolutionary Dynamics, Department of Organismic and Evolutionary Biology, Department of Mathematics, Harvard University, 5Department of Applied Mathematics, Harvard University, 6Department of Physics, Massachusetts Institute of Technology, 7Department of Systems Biology, Harvard Medical School, 8Department of Biology, Massachusetts Institute of Technology
* These authors contributed equally

Chapters

Summary
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

Hi-C metoden tillåter objektiva, genomet hela identifiering av kromatin interaktioner (1). Hi-C par närhet ligation och massivt parallella sekvensering. Den resulterande data kan användas för att studera genomiska arkitektur på flera skalor: första resultaten identifierade funktioner som kromosom territorier, segregering av öppna och slutna kromatin och kromatinstrukturen på megabase skala.

Tags

Cellbiologi kromosom konformation fånga kromatinstrukturen Illumina Paired End-sekvensering polymer fysik.
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter