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Journal / Biology / 결함 Pms2, ERCC1, Ku86, 결장암을 진행하는 동안 필드 결함에…
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Biology

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JoVE Journal Biology
결함 Pms2, ERCC1, Ku86, 결장암을 진행하는 동안 필드 결함에 CcOI
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결함 Pms2, ERCC1, Ku86, 결장암을 진행하는 동안 필드 결함에 CcOI

Article DOI: 10.3791/1931-v • 28:16 min • July 28th, 2010
July 28th, 2010 •
1, 1, 1, 1, 1, 1, 2,3, 1,4, 3, 5, 5, 5, 1
1Department of Cell Biology and Anatomy, College of Medicine, University of Arizona, Tucson, 2Southern Arizona Veterans Affairs Health Care System, Tucson, AZ, 3Department of Surgery, College of Medicine, University of Arizona, Tucson, 4Biomedical Diagnostics and Research, Tucson, AZ, 5Department of Medicine, College of Medicine, University of Arizona, Tucson

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Pms2 및 / 또는 전체 crypts에서 ERCC1의 감소 / 결석 표현 가능성 colonic adenocarcinomas, 높은 mutability 암하는 모습으로 현장 결함의 기초의 각 측면에 10cm 이내에 자주 이벤트입니다. Ku86 또는 CcOI의 결핍증은 훨씬 덜 자주 이러한 필드 결함에 있습니다.

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세포 생물학 제 41 DNA 수리 Apoptosis 필드 결함 결장암 Pms2 ERCC1 시토크롬 C 산화 효소의 Subunit I Ku86 Immunohistochemistry 암 절제술
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