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PAR -クリップ - RNA結合タンパク質のトランスクリプトーム全体の結合部位を同定する方法
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Article
DOI:
10.3791/2034-v
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12:24 min
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July 2nd, 2010
PAR -クリップ - RNA結合タンパク質のトランスクリプトーム全体の結合部位を同定する方法
July 2nd, 2010
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Markus Hafner1, Markus Landthaler2, Lukas Burger3, Mohsen Khorshid3, Jean Hausser4, Philipp Berninger4, Andrea Rothballer1, Manuel Ascano1, Anna-Carina Jungkamp2, Mathias Munschauer2, Alexander Ulrich1, Greg S. Wardle1, Scott Dewell5, Mihaela Zavolan3, Thomas Tuschl1
1Howard Hughes Medical Institute, Laboratory of RNA Molecular Biology, Rockefeller University, 2Berlin Institute for Medical Systems Biology, Max-Delbrück-Center for Molecular Medicine, 3Biozentrum der Universität Basel and Swiss Institute of Bioinformatics (SIB), 4Biozentrum der Universität Basel and Swiss Institute of Bioinformatics (SIB), 5Genomics Resource Center, Rockefeller University
Chapters
Summary
Please note that all translations are automatically generated.
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RNA転写物は、トランス作用RNA結合タンパク質(RBPs)の多数によって媒介される大規模な転写後調節の対象となります。ここでは正確にとトランスクリプトーム全体の規模でRBPsのRNA結合部位を同定するために一般化の方法を提示する。